Evidence map›Paper›PMID 24192980›Full record

ArticleEuropean radiology2014

Automated quantification of epicardial adipose tissue using CT angiography: evaluation of a prototype software.

James V Spearman, Felix G Meinel, U Joseph Schoepf, Paul Apfaltrer, Justin R Silverman, Aleksander W Krazinski, Christian Canstein, Carlo Nicola De Cecco, Philip Costello, Lucas L Geyer

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Article in European radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

James V SpearmanDepartment of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower 25 Courtenay Drive, Charleston, SC, 29425-2260, USA.
Felix G Meinel
U Joseph Schoepf
Paul Apfaltrer
Justin R Silverman
Aleksander W Krazinski
Christian Canstein
Carlo Nicola De Cecco
Philip Costello
Lucas L Geyer

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study evaluated the performance of a novel automated software tool for epicardial fat volume (EFV) quantification compared to a standard manual technique at coronary CT angiography (cCTA).

methodscCTA data sets of 70 patients (58.6 ± 12.9 years, 33 men) were retrospectively analysed using two different post-processing software applications. Observer 1 performed a manual single-plane pericardial border definition and EFVM segmentation (manual approach). Two observers used a software program with fully automated 3D pericardial border definition and EFVA calculation (automated approach). EFV and time required for measuring EFV (including software processing time and manual optimization time) for each method were recorded. Intraobserver and interobserver reliability was assessed on the prototype software measurements. T test, Spearman's rho, and Bland-Altman plots were used for statistical analysis.

resultsThe final EFVA (with manual border optimization) was strongly correlated with the manual axial segmentation measurement (60.9 ± 33.2 mL vs. 65.8 ± 37.0 mL, rho = 0.970, P < 0.001). A mean of 3.9 ± 1.9 manual border edits were performed to optimize the automated process. The software prototype required significantly less time to perform the measurements (135.6 ± 24.6 s vs. 314.3 ± 76.3 s, P < 0.001) and showed high reliability (ICC > 0.9).

conclusionsAutomated EFVA quantification is an accurate and time-saving method for quantification of EFV compared to established manual axial segmentation methods. KEY POINTS: • Manual epicardial fat volume quantification correlates with risk factors but is time-consuming. • The novel software prototype automates measurement of epicardial fat volume with good accuracy. • This novel approach is less time-consuming and could be incorporated into clinical workflow.

Indexed as

SoftwareAdipose TissueCoronary AngiographyCoronary Artery DiseaseFemaleHumansImaging, Three-DimensionalMaleMiddle AgedObserver VariationPericardiumRadiographic Image Interpretation, Computer-AssistedReproducibility of ResultsRetrospective StudiesSoftware DesignTomography, X-Ray Computed

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.