ArticlePlant physiology2014
Terpene down-regulation triggers defense responses in transgenic orange leading to resistance against fungal pathogens.
Article in Plant physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.
- Unveiling crosstalk between abiotic and biotic stress responses in soybean (Glycine max) using integrative RNA-Seq meta-analysis.Molecular genetics and genomics : MGG · 2025Pooled it
- Field resistance of orange fruit to citrus black spot and citrus canker in D-limonene synthase downregulated trees.Pest management science · 2026Article
- Integrated metabolomic and transcriptomic profiling uncovers a citrus terpene synthase withFrontiers in plant science · 2026Article
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- Single-step genome-wide association study for susceptibility toFrontiers in plant science · 2023Article
- Advances in understanding Norway spruce natural resistance to needle bladder rust infection: transcriptional and secondary metabolites profiling.BMC genomics · 2022Article
- Generation of Transfer-DNA-Free Base-Edited Citrus Plants.Frontiers in plant science · 2022Article
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- Zanthoxylum-specific whole genome duplication and recent activity of transposable elements in the highly repetitive paleotetraploid Z. bungeanum genome.Horticulture research · 2021Article
- MrTPS3 and MrTPS20 Are Responsible for β-Caryophyllene and α-Pinene Production, Respectively, in Red Bayberry (Frontiers in plant science · 2021Article
- Sensory-Directed Genetic and Biochemical Characterization of Volatile Terpene Production in Kiwifruit.Plant physiology · 2020Article
- Integrated Transcriptomic and Un-Targeted Metabolomics Analysis Reveals Mulberry Fruit (International journal of molecular sciences · 2020Article
- Transcriptomic Analysis of Orange Fruit Treated with Pomegranate Peel Extract (PGE).Plants (Basel, Switzerland) · 2019Article
- Link between carrot leaf secondary metabolites and resistance to Alternaria dauci.Scientific reports · 2018Article
- Engineering d-limonene synthase down-regulation in orange fruit induces resistance against the fungus Phyllosticta citricarpa through enhanced accumulation of monoterpene alcohols and activation of defence.Molecular plant pathology · 2018Article
- Integrated transcriptomic and metabolomic analyses of a wax deficient citrus mutant exhibiting jasmonic acid-mediated defense against fungal pathogens.Horticulture research · 2018Article
- A comprehensive proteomic analysis of elaioplasts from citrus fruits reveals insights into elaioplast biogenesis and function.Horticulture research · 2018Article
- Monoterpenes Support Systemic Acquired Resistance within and between Plants.The Plant cell · 2017Article
- Genomic Analysis of Terpene Synthase Family and Functional Characterization of Seven Sesquiterpene Synthases fromFrontiers in plant science · 2017Article
- Direct suppression of a rice bacterial blight (Xanthomonas oryzae pv. oryzae) by monoterpene (S)-limonene.Protoplasma · 2016Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Terpenoid volatiles are isoprene compounds that are emitted by plants to communicate with the environment. In addition to their function in repelling herbivores and attracting carnivorous predators in green tissues, the presumed primary function of terpenoid volatiles released from mature fruits is the attraction of seed-dispersing animals. Mature oranges (Citrus sinensis) primarily accumulate terpenes in peel oil glands, with d-limonene accounting for approximately 97% of the total volatile terpenes. In a previous report, we showed that down-regulation of a d-limonene synthase gene alters monoterpene levels in orange antisense (AS) fruits, leading to resistance against Penicillium digitatum infection. A global gene expression analysis of AS versus empty vector (EV) transgenic fruits revealed that the down-regulation of d-limonene up-regulated genes involved in the innate immune response. Basal levels of jasmonic acid were substantially higher in the EV compared with AS oranges. Upon fungal challenge, salicylic acid levels were triggered in EV samples, while jasmonic acid metabolism and signaling were drastically increased in AS orange peels. In nature, d-limonene levels increase in orange fruit once the seeds are fully viable. The inverse correlation between the increase in d-limonene content and the decrease in the defense response suggests that d-limonene promotes infection by microorganisms that are likely involved in facilitating access to the pulp for seed-dispersing frugivores.
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