Evidence map›Paper›PMID 24189696›Full record

ArticleNature communications2013

Subnanoradian X-ray phase-contrast imaging using a far-field interferometer of nanometric phase gratings.

Han Wen, Andrew A Gomella, Ajay Patel, Susanna K Lynch, Nicole Y Morgan, Stasia A Anderson, Eric E Bennett, Xianghui Xiao, Chian Liu, Douglas E Wolfe

Abstract read
In one paragraph

Article in Nature communications, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Advanced X-Ray Imaging Technology.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Han WenNational Institutes of Health, Bethesda, Maryland, USA.
Andrew A Gomella
Ajay Patel
Susanna K Lynch
Nicole Y Morgan
Stasia A Anderson
Eric E Bennett
Xianghui Xiao
Chian Liu
Douglas E Wolfe

Funding

NHLBI Animal Program DivisionZIGHL006020 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CLARK, TANNIA · 2009 to 2025
$47.3M
Microfabrication for Biomedical ResearchZICEB000012 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI MORGAN, NICOLE Y · 2010 to 2025
$11.3M
X-Ray Phase Contrast Imaging Concepts and SystemsZIAHL004606 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI WEN, HAN · 2009 to 2022
$10.1M
Animal MRI/Imaging CoreZICHL005909 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI ANDERSON, STASIA · 2010 to 2019
$5.3M
6 · The paper itself

Abstract

Hard X-ray phase-contrast imaging characterizes the electron density distribution in an object without the need for radiation absorption. The power of phase contrast to resolve subtle changes, such as those in soft tissue structures, lies in its ability to detect minute refractive bending of X-rays. Here we report a far-field, two-arm interferometer based on the new nanometric phase gratings, which can detect X-ray refraction with subnanoradian sensitivity, and at the same time overcomes the fundamental limitation of ultra-narrow bandwidths (Δλ/λ~10⁻⁴) of the current, most sensitive methods based on crystal interferometers. On a 1.5% bandwidth synchrotron source, we demonstrate clear visualization of blood vessels in unstained mouse organs in simple projection views, with over an order-of-magnitude higher phase contrast than current near-field grating interferometers.

Indexed as

AnimalsBlood VesselsDrosophila melanogasterInterferometryKidneyMaleMiceMice, Inbred C57BLSynchrotronsTomography, X-Ray ComputedX-Rays

Identifiers

PMID24189696
PMCPMC3831282

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.