Evidence map›Paper›PMID 24189620›Full record

ArticleThe Journal of general virology2014

Co-circulation of enteroviruses between apes and humans.

Heli Harvala, Dung Van Nguyen, Chloe McIntyre, Steve Ahuka-Mundeke, Eitel Mpoudi Ngole, Eric Delaporte, Martine Peeters, Peter Simmonds

Abstract read
In one paragraph

Article in The Journal of general virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Microorganisms · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Heli HarvalaCentre for Immunology, Infection and Evolution, University of Edinburgh, Edinburgh, UK.
Dung Van NguyenCentre for Immunology, Infection and Evolution, University of Edinburgh, Edinburgh, UK.
Chloe McIntyreCentre for Immunology, Infection and Evolution, University of Edinburgh, Edinburgh, UK.
Steve Ahuka-MundekeInstitute National de Recherche Biomédicales and Service de Microbiologie, Cliniques Universitaires de Kinshasa, Kinshasa, Democratic Republic of Congo.
Eitel Mpoudi NgoleProjet Prévention du Sida au Cameroun (PRESICA) and Virology Laboratory IMPM/CRMER/IRD, Yaoundé, Cameroon.
Eric DelaporteUMI233, Institute de Recherche pour le Développement and University of Montpellier, Montpellier, France.
Martine PeetersUMI233, Institute de Recherche pour le Développement and University of Montpellier, Montpellier, France.
Peter SimmondsCentre for Immunology, Infection and Evolution, University of Edinburgh, Edinburgh, UK.

Funding

Natural SIV Reservoirs and Human Zoonotic RiskR01AI050529 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HAHN, BEATRICE H · 2001 to 2022
$6.1M
Natural SIV Reservoirs and Human Zoonotic RiskR37AI050529 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HAHN, BEATRICE H · 2008 to 2017
$5.7M
NIAID NIH HHS R01 AI050529NIAID NIH HHS R01 AI 50529NIAID NIH HHS R37 AI050529Wellcome Trust 095831
6 · The paper itself

Abstract

A total of 139 stool samples from wild chimpanzees, gorillas and bonobos in Cameroon and Democratic Republic of Congo (DRC) were screened for enteroviruses (EVs) by reverse transcription PCR. Enterovirus RNA was detected in 10 % of samples, comprising eight from 58 sampled chimpanzees (13.8 %), one from 40 bonobos (2.5 %) and five from 40 gorillas (12.2 %). Three viruses isolated from chimpanzees grouped with human isolate EV-A89 and four (four chimpanzees, one gorilla) represented a newly identified type, EV-A119. These species A virus types overlapped with those circulating in human populations in the same area. The remaining six strains comprised a new species D type, EV-D120, infecting one chimpanzee and four gorillas, and a single EV variant infecting a bonobo that was remarkably divergent from other EVs and potentially constitutes a new enterovirus species. The study demonstrates both the circulation of genetically divergent EV variants in apes and monkeys as well as those shared with local human populations.

Indexed as

AnimalsCameroonCluster AnalysisDemocratic Republic of the CongoEnterovirusEnterovirus InfectionsFecesGenotypeHominidaeHumansMolecular Sequence DataPhylogenyPrimate DiseasesReverse Transcriptase Polymerase Chain ReactionRNA, ViralSequence Analysis, DNARNA, Viral

Identifiers

PMID24189620
PMCPMC4093782

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.