Evidence map›Paper›PMID 24189592›Full record

ArticleAnnals of internal medicine2013

Participatory medicine: A home score for streptococcal pharyngitis enabled by real-time biosurveillance: a cohort study.

Andrew M Fine, Victor Nizet, Kenneth D Mandl

Open access · bronzeAbstract read
In one paragraph

Article in Annals of internal medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Comparison of Centor and McIsaac scores in primary care: a meta-analysis over multiple thresholds.The British journal of general practice : the journal of the Royal College of General Practitioners · 2020
    Pooled it
  2. Clinical practice guideline: tonsillitis I. Diagnostics and nonsurgical management.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016
    Guideline
  3. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Andrew M Fine
Victor Nizet
Kenneth D Mandl
University of Montana · US

Funding

GAS Switch from Colonizing Bacterium to Invasive PathogenR01AI077780 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NIZET, VICTOR · 2008 to 2019
$3.8M
Disease Surveillance in Real Time: Geotemporal MethodsR01LM007677 · NLM · CHILDREN'S HOSPITAL BOSTON · PI MANDL, KENNETH D. · 2003 to 2009
$2.9M
Evolving Clinical Information Libraries: Contextualizing Evidence Based MedicineG08LM009778 · NLM · HARVARD MEDICAL SCHOOL · PI MANDL, KENNETH D. · 2008 to 2010
$356k
NIAID NIH HHS R01 AI077780NLM NIH HHS 1G08LM009778NLM NIH HHS G08 LM009778NLM NIH HHS R01 LM007677PHITPO CDC HHS K01 HK000055PHITPO CDC HHS K01HK000055PHITPO CDC HHS P01 HK000088PHITPO CDC HHS P01HK000088
6 · The paper itself

Abstract

backgroundConsensus guidelines recommend against testing or treating adults at low risk for group A streptococcal (GAS) pharyngitis.

objectiveTo help patients decide when to visit a clinician for the evaluation of sore throat.

designRetrospective cohort study.

settingA national chain of retail health clinics. PATIENTS: 71 776 patients aged 15 years or older with pharyngitis who visited a clinic from September 2006 to December 2008. MEASUREMENTS: The authors created a score using information from patient-reported clinical variables plus the incidence of local disease and compared it with the Centor score and other traditional scores that require clinician-elicited signs.

resultsIf patients aged 15 years or older with sore throat did not visit a clinician when the new score estimated the likelihood of GAS pharyngitis to be less than 10% instead of having clinicians manage their symptoms following guidelines that use the Centor score, 230 000 visits would be avoided in the United States each year and 8500 patients with GAS pharyngitis who would have received antibiotics would not be treated with them. LIMITATION: Real-time information about the local incidence of GAS pharyngitis, which is necessary to calculate the new score, is not currently available.

conclusionA patient-driven approach to pharyngitis diagnosis that uses this new score could save hundreds of thousands of visits annually by identifying patients at home who are unlikely to require testing or treatment. PRIMARY FUNDING SOURCE: Centers for Disease Control and Prevention and the National Library of Medicine, National Institutes of Health.

Indexed as

Patient ParticipationStreptococcus pyogenesAdolescentAdultDecision Support TechniquesFemaleHumansIncidenceMaleOffice VisitsPharyngitisPopulation SurveillanceRetrospective StudiesRisk AssessmentStreptococcal InfectionsUnited States

Identifiers

PMID24189592
PMCPMC3953456
OpenAlexW2024201445

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.