Evidence map›Paper›PMID 24189578›Full record

Trial reportJAMA pediatrics2014

Perioperative outcomes of adolescents undergoing bariatric surgery: the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study.

Thomas H Inge, Meg H Zeller, Todd M Jenkins, Michael Helmrath, Mary L Brandt, Marc P Michalsky, Carroll M Harmon, Anita Courcoulas, Mary Horlick, Stavra A Xanthakos and 5 more

Registry-linked trialOpen access · greenAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in JAMA pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00474318 (Teen-Longitudinal Assessment of Bariatric Surgery), which is not on this map. Cited by 130 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
130citing papers in PubMed, 4 pooled it
27.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00474318 completednot on this map

Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Research Project

TypeobservationalSponsorAnn & Robert H Lurie Children's Hospital of ChicagoRan2007 to 2024Enrolled250ConditionsObesity
3 · Its place in the literature

Who cites it

130 citing papers in PubMed, 4 syntheses or guidelines pooled it, 294 citations in OpenAlex.

  1. Experienced Weight Stigma Changes Following Bariatric Surgery: a Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Pooled it
  2. Pooled it
  3. Pediatric Obesity-Assessment, Treatment, and Prevention: An Endocrine Society Clinical Practice Guideline.The Journal of clinical endocrinology and metabolism · 2017 · on this map
    Guideline
  4. Pooled it
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70 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 1 country.

Thomas H IngeCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Meg H ZellerCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Todd M JenkinsCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Michael HelmrathCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Mary L BrandtTexas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Marc P MichalskyNationwide Children's Hospital, Columbus, Ohio.
Carroll M HarmonUniversity of Alabama at Birmingham.
Anita CourcoulasUniversity of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Mary HorlickNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Stavra A XanthakosCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Larry DolanCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Mark MitsnefesCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Sean J BarnettCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Ralph BuncherUniversity of Cincinnati, Cincinnati, Ohio.
Teen-LABS Consortium
Cincinnati Children's Hospital Medical Center · USNational Institutes of Health · USNationwide Children's Hospital · USTexas Children's Hospital · USUniversity of Alabama at Birmingham · USUniversity of Cincinnati · USUniversity of Pittsburgh Medical Center · US

Funding

UNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9M
University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
ZOLENDRONIC ACID IN CHILDREN W/ SEVERE OSTEOGENESIS IMPERFECTAM01RR000188 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI PLON, SHARON E. · 1985 to 2011
$30.6M
University of Iowa Clinical and Translational Science Program (TL1)UL1RR025755 · NCRR · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2008 to 2011
$26.3M
Stem Cell/Organoid and Genome Editing CoreP30DK078392 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI Alexander Miethke · 2007 to 2026
$24.4M
VITAMIN K DEFICIENCY IN CHOLESTATIC LIVER DISEASEM01RR008084 · NCRR · CINCINNATI CHILDRENS HOSP MED CTR · PI STRAUSS, ARNOLD W · 1994 to 2009
$20.6M
Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Research ProjectUM1DK072493 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI INGE, THOMAS HARRIS · 2011 to 2020
$10.5M
Cincinnati Center for Clinical and Translational Sciences and TrainingUL1TR000077 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E. · 2012 to 2014
$9.9M
UAB Center for Clinical and Translational Science (CCTS) UL1UL1TR000165 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2012 to 2013
$9.6M
Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) renewalUM1DK095710 · NIDDK · UNIVERSITY OF CINCINNATI · PI JENKINS, TODD M, XIE, CHANGCHUN · 2011 to 2020
$9.4M
Adolescent Bariatrics: Assessing Health Benefits & RisksU01DK072493 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI INGE, THOMAS HARRIS · 2006 to 2010
$8.7M
NCATS NIH HHS UL1 TR000005NCATS NIH HHS UL1TR000005NCATS NIH HHS UL1 TR000077NCATS NIH HHS UL1 TR000077-04NCATS NIH HHS UL1 TR000165NCATS NIH HHS UL1 TR001425NCRR NIH HHS M01 RR000188NCRR NIH HHS M01-RR00188NCRR NIH HHS M01 RR008084NCRR NIH HHS UL1 RR024153NCRR NIH HHS UL1 RR025755NCRR NIH HHS UL1RR025755NIDDK NIH HHS P30 DK078392NIDDK NIH HHS U01 DK072493NIDDK NIH HHS U01DK072493NIDDK NIH HHS UM1 DK072493NIDDK NIH HHS UM1DK072493NIDDK NIH HHS UM1 DK095710NIDDK NIH HHS UM1DK095710
6 · The paper itself

Abstract

importanceSevere obesity in childhood is a major health problem with few effective treatments. Weight-loss surgery (WLS) is being used to treat severely obese adolescents, although with very limited data regarding surgical safety for currently used, minimally invasive procedures.

objectiveTo assess the preoperative clinical characteristics and perioperative safety outcomes of severely obese adolescents undergoing WLS. DESIGN, SETTING, AND

participantsThis prospective, multisite observational study enrolled patients from February 28, 2007, through December 30, 2011. Consecutive patients aged 19 years or younger who were approved to undergo WLS (n = 277) were offered enrollment into the study at 5 academic referral centers in the United States; 13 declined participation and 22 did not undergo surgery after enrollment, thus the final analysis cohort consisted of 242 individuals. There were no withdrawals. MAIN OUTCOMES AND MEASURES: This analysis examined preoperative anthropometrics, comorbid conditions, and major and minor complications occurring within 30 days of operation. All data were collected in a standardized fashion. Reoperations and hospital readmissions were adjudicated by independent reviewers to assess relatedness to the WLS procedure.

resultsThe mean (SD) age of participants was 17.1 (1.6) years and the median body mass index (calculated as weight in kilograms divided by height in meters squared) was 50.5. Fifty-one percent demonstrated 4 or more major comorbid conditions. Laparoscopic Roux-en-Y gastric bypass, vertical sleeve gastrectomy, and adjustable gastric banding were performed in 66%, 28%, and 6% of patients, respectively. There were no deaths during the initial hospitalization or within 30 days of operation; major complications (eg, reoperation) were seen in 19 patients (8%). Minor complications (eg, readmission for dehydration) were noted in 36 patients (15%). All reoperations and 85% of readmissions were related to WLS. CONCLUSIONS AND RELEVANCE: In this series, adolescents with severe obesity presented with abundant comorbid conditions. We observed a favorable short-term complication profile, supporting the early postoperative safety of WLS in select adolescents. Further longitudinal study of this cohort will permit accurate assessment of long-term outcomes for adolescents undergoing bariatric surgery.

trial registrationclinicaltrials.gov Identifier: NCT00474318.

Indexed as

AdolescentBariatric SurgeryBody Mass IndexFemaleHumansLongitudinal StudiesMaleObesity, MorbidPostoperative ComplicationsProspective StudiesRisk FactorsTreatment OutcomeUnited StatesYoung Adult

Identifiers

PMID24189578
PMCPMC4060250
OpenAlexW2100417128

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.