ArticleThe American journal of tropical medicine and hygiene2014
High prevelance of rifampin-monoresistant tuberculosis: a retrospective analysis among Iranian pulmonary tuberculosis patients.
Article in The American journal of tropical medicine and hygiene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Prevalence and determinants of drug-resistant pulmonary tuberculosis in the MENA region: a systematic review and meta-analysis.BMJ open respiratory research · 2026Pooled it
- Variation in Mycobacterium tuberculosis population structure in Iran: a systemic review and meta-analysis.BMC infectious diseases · 2021Pooled it
- The reliability of rifampicin resistance as a proxy for multidrug-resistant tuberculosis: a systematic review of studies from Iran.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018Pooled it
- Longitudinal Analysis of Prevalence and Risk Factors of Rifampicin-Resistant Tuberculosis in Zhejiang, China.BioMed research international · 2020Trial
- Resistance characteristics of culture-positive tuberculosis from 2015 to 2022.Frontiers in public health · 2025Article
- Rifampicin-resistant tuberculosis in Iran: A systematic review and meta-analysis.Iranian journal of basic medical sciences · 2021Review
- An updated systematic review and meta-analysis onIranian journal of basic medical sciences · 2021Review
- Prevalence ofSAGE open medicine · 2021Article
- Role of Immigration in Tuberculosis Transmission to Iran: A Systematic Review.International journal of preventive medicine · 2020Review
- Rifampicin resistance among notified pulmonary tuberculosis (PTB) cases in South-Southern Nigeria.Heliyon · 2019Article
- Role of Molecular Epidemiology on Tuberculosis Control in the Middle East Countries: a Systematic Review and Meta-Analysis.Tanaffos · 2018Article
- Investigation of theIranian journal of pathology · 2018Article
- Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance.Nature genetics · 2017Article
- Rifampicin-resistantInfection and drug resistance · 2017Article
- Primary ethambutol resistance among Iranian pulmonary tuberculosis patients: a systematic review.Therapeutic advances in infectious disease · 2016Review
- Rifampin Resistance Mutations Are Associated with Broad Chemical Remodeling of Mycobacterium tuberculosis.The Journal of biological chemistry · 2016Article
- Article
- First-Line Anti-Tubercular Drug Resistance of Mycobacterium tuberculosis in IRAN: A Systematic Review.Frontiers in microbiology · 2016Review
- Early initiation of antiretroviral treatment: Challenges in the Middle East and North Africa.World journal of virology · 2015Review
- Article
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
We determined the prevalence of rifampin-monoresistant tuberculosis (RMR-TB) in Iran. Because development of RMR-TB is not common, we also identified the major risk factors associated with RMR-TB reported from different provinces of Iran. Data for 3,020 TB patients who remained or became smear positive after two, four, six, and nine months of standard first-line chemotherapy were retrospectively analyzed. Of 3,020 patients, 1,242 patients (41.1%) were culture and DNA positive for Mycobacterium tuberculosis. Of these patients, 73 (7.4%) patients had monoresistant isolates to rifampin, which was significantly higher than that for multidrug-resistant TB (5.8%). The average rate of RMR-TB in the studied population ranged from 5% to 10%. Classical investigation showed that 33.6% of patients had either a previous or family history of TB. Molecular epidemiology methods (i.e., spoligotyping and Mycobacterium interspersed repetitive unit-variable number tandem repeat), defined transmission link in three clusters (13%). These results outline the urgent need for a comprehensive plan for detection and treatment of RMR-TB cases.
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