Evidence map›Paper›PMID 24189247›Full record

ArticleAntimicrobial agents and chemotherapy2014

Derepressed transfer properties leading to the efficient spread of the plasmid encoding carbapenemase OXA-48.

Anaïs Potron, Laurent Poirel, Patrice Nordmann

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed.

  1. The genomic landscape of Klebsiella pneumoniae in Russia.World journal of microbiology & biotechnology · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Complete genome sequence of the OXA-48-producingMicrobiology resource announcements · 2024
    Article
  9. Carbapenem-Resistant NDM and OXA-48-Antibiotics (Basel, Switzerland) · 2024
    Article
  10. Article
  11. Characterization of blaInfection · 2024
    Article
  12. Article
  13. Review
  14. Combination Therapy for OXA-48 Carbapenemase-ProducingInfection and drug resistance · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Genomic characterization of an NDM-9-producingFrontiers in microbiology · 2023
    Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anaïs PotronINSERM U914, Emerging Resistance to Antibiotics, Faculté de Médecine et Université Paris-Sud, K. Bicêtre, France.
Laurent Poirel
Patrice Nordmann

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current emergence of the carbapenemase OXA-48 among Enterobacteriaceae is related to the spread of a single IncL/M-type plasmid, pOXA-48a. This plasmid harbors the blaOXA-48 gene within a composite transposon, Tn1999, which is inserted into the tir gene, encoding a transfer inhibition protein. We showed that the insertion of Tn1999 into the tir gene was involved in a higher transfer frequency of plasmid pOXA-48a. This may likely be the key factor for the successful dissemination of this plasmid.

Indexed as

Anti-Bacterial AgentsBacterial Proteinsbeta-LactamasesDNA Transposable ElementsEnterobacteriaceaePlasmidsAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasescarbapenemaseDNA Transposable Elements

Identifiers

PMID24189247
PMCPMC3910765

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.