Trial reportJournal of cardiopulmonary rehabilitation and prevention
V.O2 Kinetics and clinical factors among patients with peripheral artery disease.
Trial report in Journal of cardiopulmonary rehabilitation and prevention. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The trial behind it
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Who cites it
6 citing papers in PubMed.
- Observational
- Six-minute walk test reveals delayed oxygen uptake kinetics in ischemic cardiomyopathy.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025Article
- The role of the microcirculation and integrative cardiovascular physiology in the pathogenesis of ICU-acquired weakness.Frontiers in physiology · 2023Review
- Abnormal vibration perception threshold alters the gait features in type 2 diabetes mellitus patients.Frontiers in endocrinology · 2022Article
- Association between gait characteristics and endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease.Age (Dordrecht, Netherlands) · 2016Article
- Predictive Value of the CHAAdvances in rehabilitation science and practiceArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeTo investigate the association between oxygen uptake (V.O2) kinetics and demographic, behavioral, and clinical factors among patients with peripheral artery disease (PAD).
methodsA total of 85 PAD patients with intermittent claudication performed a constant load treadmill test, and breath-by-breath (V.e.)O2 was obtained to assess V.O2 kinetics. Demographic information, anthropometry, cardiovascular risk factors, and comorbid conditions were recorded.
resultsUsing univariate analyses, higher values of tau ([τ], i.e., slowed V.O2 kinetics) were associated with female gender, non-Caucasian race, hypertension, dyslipidemia, and age ≤66 years. Smoking, diabetes, obesity, metabolic syndrome, height, and ankle brachial index were not significantly related to V.O2 kinetics. Using multiple regression procedures, the identified predictors of slowed V.O2 kinetics were female gender (4.76 [95% CI: 1.49-8.03] seconds; P = .0049), non-Caucasian race (4.70 [95% CI: 1.29-8.12] seconds; P = .0075), hypertension (12.06 [95% CI: 8.83-15.28] seconds; P < .0001), and age ≤66 years (4.97 [95% CI: 1.95-7.99] seconds; P = .0015).
conclusionsIn PAD patients, slowed V.O2 kinetics are associated with demographic and clinical factors. The clinical significance is that female, non-Caucasian, and hypertensive PAD patients present central and/or peripheral limitations that may partially account for their walking impairment.
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