Evidence map›Paper›PMID 24189044›Full record

ArticleCell research2014

The disposable soma theory of aging in reverse.

Peter M Douglas, Andrew Dillin

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
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  8. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Peter M Douglas1] California Institute for Regenerative Medicine, Berkeley, CA 94720-3370, USA [2] Howard Hughes Medical Institute, Berkeley, CA 94720-3370, USA [3] University of California, Berkeley, CA 94720-3370, USA.
Andrew Dillin1] California Institute for Regenerative Medicine, Berkeley, CA 94720-3370, USA [2] Howard Hughes Medical Institute, Berkeley, CA 94720-3370, USA [3] University of California, Berkeley, CA 94720-3370, USA.

Funding

Neuroendocrine Coordination of Mitochondrial Stress Signaling and ProteostasisR01ES021667 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI DILLIN, ANDREW G · 2012 to 2023
$4.6M
Cell Non-Autonomous nature of the Heat Shock ResponseR00AG042495 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI DOUGLAS, PETER MAHAN · 2015 to 2017
$728k
Cell non-autonomous nature of the heat shock responseK99AG042495 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI DOUGLAS, PETER MAHAN · 2013 to 2014
$249k
NIA NIH HHS K99 AG042495NIA NIH HHS R00 AG042495NIEHS NIH HHS R01 ES021667
6 · The paper itself

Abstract

In a recent paper in Nature, Ermolaeva et al. uncover a systemic response to DNA damage in germ cells that protects somatic tissues, providing mechanistic insight into the bidirectional communication between germ line and soma.

Indexed as

DNA DamageImmunity, InnateAdaptation, PhysiologicalAnimalsCaenorhabditis elegansGerm CellsStress, Physiological

Identifiers

PMID24189044
PMCPMC3879701

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.