Evidence map›Paper›PMID 24188706›Full record

ReviewAntiviral research2013

Designing a multipurpose technology for acceptability and adherence.

Elizabeth E Tolley, Kathleen M Morrow, Derek H Owen

Abstract readReview
In one paragraph

Review in Antiviral research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elizabeth E TolleyFHI 360, Social and Behavioral Health Sciences, 2224 East Highway 54, Durham, NC 27713, United States. Electronic address: btolley@fhi360.org.
Kathleen M Morrow
Derek H Owen

Funding

Preclinical User Accptability Studies Long Acting Vaginal Gels, Intravaginal RingU19AI077289 · NIAID · IMQUEST BIOSCIENCES · PI KATZ, DAVID FRANK · 2008 to 2012
$6.7M
Linking Biophysical Functions of Microbicides to User Perception & AcceptabilityR33MH080591 · NIMH · MIRIAM HOSPITAL · PI GUTHRIE, KATE M · 2008 to 2010
$1.4M
Linking Biophysical Functions of Microbicides to User Perception & AcceptabilityR21MH080591 · NIMH · MIRIAM HOSPITAL · PI MORROW, KATHLEEN M · 2006 to 2007
$384k
NIAID NIH HHS U19 AI077289NIMH NIH HHS R21 MH080591NIMH NIH HHS R33 MH080591
6 · The paper itself

Abstract

Multipurpose Prevention Technologies (MPTs) are new tools aimed at reducing or preventing multiple and overlapping sexual and reproductive health risks faced by women and couples around the globe. While MPTs could prove more acceptable and easier to adhere to than single-purpose prevention products, continuing high rates of HIV and unintended pregnancy remind us that these new products will need to be efficacious, acceptable and effectively used to achieve a public health impact. In this paper, we describe how a range of research methods can be applied during the pre-clinical phase of product development to inform decisions related to formulation and vehicle or product delivery mechanisms, and consider how choices in product-related characteristics may influence future demand for, delivery and use of future products. We draw on examples from the development of new single-purpose HIV and contraceptive products and then extend our discussion to the development of MPTs, including vaginal rings and injections. This article is based on a presentation at the "Product Development Workshop 2013: HIV and Multipurpose Prevention Technologies," held in Arlington, Virginia on February 21-22, 2013. It forms part of a special supplement to Antiviral Research.

Indexed as

Patient ComplianceCommunicable Disease ControlContraceptionFemaleHIV InfectionsHumansMalePregnancyConjoint analysisDiscrete choice experimentsMPTsPsychometric scalesQualitative research

Identifiers

PMID24188706
PMCPMC4643455

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.