Evidence map›Paper›PMID 24188703›Full record

ReviewAntiviral research2013

Antibody-based concepts for multipurpose prevention technologies.

Kevin J Whaley, Larry Zeitlin

Abstract readReview
In one paragraph

Review in Antiviral research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Commercially available immunoglobulins contain virus neutralizing antibodies against all major genotypes of polyomavirus BK.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2015
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kevin J WhaleyMapp Biopharmaceutical, Inc., San Diego, CA, USA. Electronic address: Kevin.whaley@mappbio.com.
Larry Zeitlin

Funding

Vaginal mAB Delivery SystemsU19AI096398 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ANDERSON, DEBORAH J, MOENCH, THOMAS RAY · 2011 to 2016
$15.0M
NIAID NIH HHS U19 AI096398NIAID NIH HHS U19AI096398
6 · The paper itself

Abstract

Because of the versatility and specificity of monoclonal antibodies, they are candidates for multipurpose prevention technologies when formulated as topical (gels, films, rings) or injectable drugs and as vaccines. This review focuses on antibody-based proof of concept studies for the human immunodeficiency virus, herpes simplex virus and sperm. Opportunities and challenges in antibody evasion/resistance, manufacturing, regulatory, and pharmacoeconomics are discussed. This article is based on a presentation at the "Product Development Workshop 2013: HIV and Multipurpose Prevention Technologies," held in Arlington, Virginia on February 21-22, 2013. It forms part of a special supplement to Antiviral Research.

Indexed as

AnimalsAntibodies, ViralAntiviral AgentsHerpes SimplexHIV-1HIV InfectionsHumansSimplexvirusAntibodies, ViralAntiviral AgentsHerpes simplex virusHuman immunodeficiency virusMulti-antibodyMultipurpose prevention technologiesSperm

Identifiers

PMID24188703
PMCPMC3933545

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.