ReviewTrends in neurosciences2013
Basal ganglia output to the thalamus: still a paradox.
Review in Trends in neurosciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
59 citing papers in PubMed.
- Entrained cortical delta-spindle activity, not periodic synchrony, prevents arousal by NREM thalamic bursts.Communications biology · 2026Article
- Posterior Inferior Cerebellar Artery Infarct Associated With Cervical Dystonia: A Case Report.Cureus · 2025Article
- Control Principles of Neural Dynamics Revealed by the Neurobiology of Timing.Annual review of neuroscience · 2025Review
- Article
- A cortico-subcortical loop for motor control via the pontine reticular formation.Cell reports · 2025Article
- Striatal cell-type specific stability and reorganization underlying agency and habit.bioRxiv : the preprint server for biology · 2025Article
- Article
- Modulation of alpha oscillations by attention is predicted by hemispheric asymmetry of subcortical regions.eLife · 2024Article
- Article
- Evolution of schooling drives changes in neuroanatomy and motion characteristics across predation contexts in guppies.Nature communications · 2023Article
- Remembrance of things perceived: Adding thalamocortical function to artificial neural networks.Frontiers in integrative neuroscience · 2023Review
- Solving brain circuit function and dysfunction with computational modeling and optogenetic fMRI.Science (New York, N.Y.) · 2022Review
- Optogenetic activation of the inhibitory nigro-collicular circuit evokes contralateral orienting movements in mice.Cell reports · 2022Article
- Post-Inhibitory Rebound Firing of Dorsal Root Ganglia Neurons.Journal of pain research · 2022Article
- Comparison of Sensory Observation and Somatosensory Stimulation in Mirror Neurons and the Sensorimotor Network: A Task-Based fMRI Study.Frontiers in neurology · 2022Article
- Dystonia as a Presenting Feature of Acute Ischemic Stroke: A Case Report and Literature Review.Cureus · 2021Article
- Computational models link cellular mechanisms of neuromodulation to large-scale neural dynamics.Nature neuroscience · 2021Review
- Neuronal Activity of Pallidal Versus Cerebellar Receiving Thalamus in Patients with Cervical Dystonia.Cerebellum (London, England) · 2021Article
- Unexpected Sounds Nonselectively Inhibit Active Visual Stimulus Representations.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Revisiting the "Paradox of Stereotaxic Surgery": Insights Into Basal Ganglia-Thalamic Interactions.Frontiers in systems neuroscience · 2021Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The basal ganglia (BG)-recipient thalamus controls motor output but it remains unclear how its activity is regulated. Several studies report that thalamic activation occurs via disinhibition during pauses in the firing of inhibitory pallidal inputs from the BG. Other studies indicate that thalamic spiking is triggered by pallidal inputs via post-inhibitory 'rebound' calcium spikes. Finally excitatory cortical inputs can drive thalamic activity, which becomes entrained, or time-locked, to pallidal spikes. We present a unifying framework where these seemingly distinct results arise from a continuum of thalamic firing 'modes' controlled by excitatory inputs. We provide a mechanistic explanation for paradoxical pallidothalamic coactivations observed during behavior that raises new questions about what information is integrated in the thalamus to control behavior.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.