Evidence map›Paper›PMID 24188126›Full record

ArticleEmerging infectious diseases2013

CTX-M β-lactamase-producing Klebsiella pneumoniae in suburban New York City, New York, USA.

Guiqing Wang, Tiangui Huang, Pavan Kumar Makam Surendraiah, Kemeng Wang, Rashida Komal, Jian Zhuge, Chian-Ru Chern, Alexander A Kryszuk, Cassidy King, Gary P Wormser

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Hypervirulent and Drug-ResistantInternational journal of general medicine · 2026
    Review
  4. Circulation of ESBL-producingFrontiers in public health · 2026
    Article
  5. Article
  6. Article
  7. First report of aFrontiers in cellular and infection microbiology · 2024
    Article
  8. Article
  9. NDM-5-carrying3 Biotech · 2023
    Article
  10. Extended-Spectrum Beta-Lactamases ProducingAntibiotics (Basel, Switzerland) · 2022
    Review
  11. Identification of CTX-M Type ESBLPathogens (Basel, Switzerland) · 2021
    Article
  12. Article
  13. Distribution of NDM1 Carbapenemase-ProducingInfection and drug resistance · 2020
    Article
  14. Review
  15. Genomic Diversity, Virulence, and Antimicrobial Resistance ofApplied and environmental microbiology · 2019
    Article
  16. Prevalence ofIranian journal of medical sciences · 2018
    Review
  17. Phenotypic and molecular characterization ofNew microbes and new infections · 2018
    Article
  18. Article
  19. Prevalence ofAdvanced biomedical research · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Guiqing Wang
Tiangui Huang
Pavan Kumar Makam Surendraiah
Kemeng Wang
Rashida Komal
Jian Zhuge
Chian-Ru Chern
Alexander A Kryszuk
Cassidy King
Gary P Wormser

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CTX-M extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae isolates are infrequently reported in the United States. In this study, we analyzed nonduplicate ESBL-producing K. pneumoniae and Escherichia coli clinical isolates collected during 2005-2012 at a tertiary care medical center in suburban New York City, USA, for the presence of blaCTX-M, blaSHV, blaTEM, and blaKPC genes. Despite a high prevalence of blaCTX-M genes in ESBL-producing E. coli since 2005, blaCTX-M genes were not detected in K. pneumoniae until 2009. The prevalence of CTX-M-producing K. pneumoniae increased significantly over time from 1.7% during 2005-2009 to 26.4% during 2010-2012 (p<0.0001). CTX-M-15 was the dominant CTX-M genotype. Pulsed-field gel electrophoresis and multilocus sequence typing revealed high genetic heterogeneities in CTX-M-producing K. pneumoniae isolates. This study demonstrates the recent emergence and polyclonal spread of multidrug resistant CTX-M-producing K. pneumoniae isolates among patients in a hospital setting in the United States.

Indexed as

Suburban PopulationAdultAgedbeta-LactamasesEscherichia coliFemaleGenotypeHumansKlebsiella InfectionsKlebsiella pneumoniaeMaleMicrobial Sensitivity TestsMiddle AgedMultilocus Sequence TypingNew York CityPhylogenybeta-Lactamasesantimicrobial resistancebacteriabeta-lactamases CTX-M-15Escherichia coliextended-spectrum beta-lactamasesKlebsiella pneumoniaemultilocus sequence typingpulsed-field gel electrophoresis

Identifiers

PMID24188126
PMCPMC3837662

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.