Evidence map›Paper›PMID 24187566›Full record

ReviewClinical & developmental immunology2013

N-terminal Plasmodium vivax merozoite surface protein-1, a potential subunit for malaria vivax vaccine.

Fernanda G Versiani, Maria E Almeida, Luis A Mariuba, Patricia P Orlandi, Paulo A Nogueira

Abstract readReview
In one paragraph

Review in Clinical & developmental immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Temporal Changes in the Genetic Diversity ofPathogens (Basel, Switzerland) · 2021
    Article
  4. Review
  5. Heterogeneous Network Model to Identify Potential Associations BetweenInternational journal of molecular sciences · 2020
    Article
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  8. Article
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  11. Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fernanda G VersianiUniversidade Federal do Amazonas, Avenida General Rodrigo Octávio Jordão Ramos 3000, Campus Universitário, Coroado I, 69077-000 Manaus, AM, Brazil.
Maria E Almeida
Luis A Mariuba
Patricia P Orlandi
Paulo A Nogueira

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human malaria is widely distributed in the Middle East, Asia, the western Pacific, and Central and South America. Plasmodium vivax started to have the attention of many researchers since it is causing diseases to millions of people and several reports of severe malaria cases have been noticed in the last few years. The lack of in vitro cultures for P. vivax represents a major delay in developing a functional malaria vaccine. One of the major candidates to antimalarial vaccine is the merozoite surface protein-1 (MSP1), which is expressed abundantly on the merozoite surface and capable of activating the host protective immunity. Studies have shown that MSP-1 possesses highly immunogenic fragments, capable of generating immune response and protection in natural infection in endemic regions. This paper shows humoral immune response to different proteins of PvMSP1 and the statement of N-terminal to be added to the list of potential candidates for malaria vivax vaccine.

Indexed as

HumansMalaria VaccinesMalaria, VivaxMerozoite Surface Protein 1Multiprotein ComplexesPlasmodium vivaxProtein BindingProtein Interaction Domains and MotifsVaccines, SubunitMalaria VaccinesMerozoite Surface Protein 1Multiprotein ComplexesVaccines, Subunit

Identifiers

PMID24187566
PMCPMC3804292

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.