Evidence map›Paper›PMID 24187564›Full record

ReviewClinical & developmental immunology2013

Thymic regulatory T cell development: role of signalling pathways and transcription factors.

Mark Engel, Tom Sidwell, Ajithkumar Vasanthakumar, George Grigoriadis, Ashish Banerjee

Abstract readReview
In one paragraph

Review in Clinical & developmental immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mark EngelCentre for Inflammatory Diseases, Monash Medical Centre, Southern Clinical School, Monash University, Clayton, VIC 3168, Australia.
Tom Sidwell
Ajithkumar Vasanthakumar
George Grigoriadis
Ashish Banerjee

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regulatory T cells (Tregs) are a subset of CD4 T cells that are key mediators of immune tolerance. Most Tregs develop in the thymus. In this review we summarise recent findings on the role of diverse signalling pathways and downstream transcription factors in thymic Treg development.

Indexed as

Signal TransductionCD28 AntigensDNA MethylationForkhead Transcription FactorsGene Expression RegulationHumansReceptors, Antigen, T-CellReceptors, Interleukin-2Thymus GlandT-Lymphocytes, RegulatoryTranscription FactorsTranscription, GeneticCD28 AntigensForkhead Transcription FactorsFOXP3 protein, humanReceptors, Antigen, T-CellReceptors, Interleukin-2Transcription Factors

Identifiers

PMID24187564
PMCPMC3803129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.