ArticleFrontiers in aging neuroscience2013
EEG upper/low alpha frequency power ratio relates to temporo-parietal brain atrophy and memory performances in mild cognitive impairment.
Article in Frontiers in aging neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Source-space EEG alpha activity reveals brain age gaps due to neurodegeneration and disparity.Communications biology · 2026Article
- Decoding the mechanisms of amyloid-β in synaptic toxicity.Journal of Alzheimer's disease : JAD · 2026Review
- Multimodal neuroimaging and electrophysiological signatures in amnestic mild cognitive impairment with different amyloid-β deposition status: correlations with cognitive function and diagnostic value.Frontiers in aging neuroscience · 2026Article
- EEG alpha/beta features as a biomarker for quantifying pain in patients with lumbar disk herniation.Frontiers in neuroscience · 2025Article
- Cognitive, psychological, and physiological effects of a web-based mindfulness intervention in older adults during the COVID-19 pandemic: an open study.BMC geriatrics · 2024Article
- Do try this at home: Age prediction from sleep and meditation with large-scale low-cost mobile EEG.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Article
- Increased neurocardiological interplay after mindfulness meditation: a brain oscillation-based approach.Frontiers in human neuroscience · 2023Article
- Biophysical mechanism underlying compensatory preservation of neural synchrony over the adult lifespan.Communications biology · 2022Article
- Alpha3/alpha2 power ratios relate to performance on a virtual reality shopping task in ageing adults.Frontiers in aging neuroscience · 2022Article
- Sleep EEG-Based Approach to Detect Mild Cognitive Impairment.Frontiers in aging neuroscience · 2022Article
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- Changes of Functional and Directed Resting-State Connectivity Are Associated with Neuronal Oscillations, ApoE Genotype and Amyloid Deposition in Mild Cognitive Impairment.Frontiers in aging neuroscience · 2017Article
- Progranulin Mutations Affects Brain Oscillatory Activity in Fronto-Temporal Dementia.Frontiers in aging neuroscience · 2016Article
- Adaptations of Prefrontal Brain Activity, Executive Functions, and Gait in Healthy Elderly Following Exergame and Balance Training: A Randomized-Controlled Study.Frontiers in aging neuroscience · 2016Article
- Electroencephalography-driven approach to prodromal Alzheimer's disease diagnosis: from biomarker integration to network-level comprehension.Clinical interventions in aging · 2016Article
- Conversion of mild cognitive impairment patients in Alzheimer's disease: prognostic value of Alpha3/Alpha2 electroencephalographic rhythms power ratio.Alzheimer's research & therapy · 2015Article
- Mild Cognitive Impairment: Structural, Metabolical, and Neurophysiological Evidence of a Novel EEG Biomarker.Frontiers in neurology · 2015Review
- Understanding early dementia: EEG, MRI, SPECT and memory evaluation.Translational neuroscience · 2015Article
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5 authors.
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Abstract
objectiveTemporo-parietal cortex thinning is associated to mild cognitive impairment (MCI) due to Alzheimer disease (AD). The increase of EEG upper/low alpha power ratio has been associated with AD-converter MCI subjects. We investigated the association of alpha3/alpha2 ratio with patterns of cortical thickness in MCI. MATERIALS AND
methodsSeventy-four adult subjects with MCI underwent clinical and neuropsychological evaluation, electroencephalogram (EEG) recording and high resolution 3D magnetic resonance imaging. Alpha3/alpha2 power ratio as well as cortical thickness was computed for each subject. Three MCI groups were detected according to increasing tertile values of upper/low alpha power ratio. Difference of cortical thickness among the groups was estimated. Pearson's r was used to assess the topography of the correlation between cortical thinning and memory impairment.
resultsHigh upper/low alpha power ratio group had total cortical gray matter volume reduction of 471 mm(2) than low upper/low alpha power ratio group (p < 0.001). Upper/low alpha group showed a similar but less marked pattern (160 mm(2)) of cortical thinning when compared to middle upper/low alpha power ratio group (p < 0.001). Moreover, high upper/low alpha group had wider cortical thinning than other groups, mapped to the Supramarginal and Precuneus bilaterally. Finally, in high upper/low alpha group temporo-parietal cortical thickness was correlated to memory performance. No significant cortical thickness differences was found between middle and low alpha3/alpha2 power ratio groups.
conclusionHigh EEG upper/low alpha power ratio was associated with temporo-parietal cortical thinning and memory impairment in MCI subjects. The combination of EEG upper/low alpha ratio and cortical thickness measure could be useful for identifying individuals at risk for progression to AD dementia and may be of value in clinical context.
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