ReviewPhysiology (Bethesda, Md.)2013
Emphysema and mechanical stress-induced lung remodeling.
Review in Physiology (Bethesda, Md.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed.
- Real-time single-particle imaging of functional lungs reveals mosaic-like patterns of aerosol deposition in alveoli.Nature biomedical engineering · 2026Article
- Network-Associated Mechanotransduction in Health and Disease.Results and problems in cell differentiation · 2026Review
- Mechanical Forces and Mechanotransduction in COPD: Pathogenesis, Clinical Phenotypes, and Therapeutic Implications.International journal of chronic obstructive pulmonary disease · 2026Review
- Effective-Component Compatibility of Bufei Yishen Formula Alleviates Alveolar Epithelial Barrier Damage in COPD Through Inhibition of p38 MAPK Phosphorylation.International journal of chronic obstructive pulmonary disease · 2026Article
- The importance of mechanical forces in chronic respiratory diseases.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Imaging the extracellular matrix structure and remodeling in healthy, fibrotic, and emphysematous human precision-cut lung slices.Respiratory research · 2025Article
- Novel murine partial tracheal occlusion model with altered respiratory dynamics.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- Pulmonary Biomechanics in COPD: Imaging Techniques and Clinical Applications.Journal of biomechanical engineering · 2025Review
- Pulmonary Emphysema: Current Understanding of Disease Pathogenesis and Therapeutic Approaches.Biomedicines · 2025Review
- Mechanically Affected Lung and Progression of Emphysema.American journal of respiratory and critical care medicine · 2025Article
- Beyond classical collagen: basement membrane collagen IV in age-associated lung diseases.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- Fibrotic and emphysematous murine lung mechanics under negative-pressure ventilation.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- Elastin Peptides as a Potential Disease Vector in the Pathogenesis of Pulmonary Emphysema: An Investigation of This Hypothesis.Life (Basel, Switzerland) · 2025Article
- Piezo channels modulate human lung fibroblast function.American journal of physiology. Lung cellular and molecular physiology · 2024Article
- Review
- Reply to TepperAmerican journal of respiratory and critical care medicine · 2024Article
- Antenatal Endotoxin Induces Dysanapsis in Experimental Bronchopulmonary Dysplasia.American journal of respiratory cell and molecular biology · 2024Article
- Anti-CELA1 antibody KF4 prevents emphysema by inhibiting stretch-mediated remodeling.JCI insight · 2024Article
- Integrating mechanical cues with engineered platforms to explore cardiopulmonary development and disease.iScience · 2023Review
- Crystal ribcage: a platform for probing real-time lung function at cellular resolution.Nature methods · 2023Article
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Authors and funding
6 authors.
Funding
Abstract
Transpulmonary pressure and the mechanical stresses of breathing modulate many essential cell functions in the lung via mechanotransduction. We review how mechanical factors could influence the pathogenesis of emphysema. Although the progression of emphysema has been linked to mechanical rupture, little is known about how these stresses alter lung remodeling. We present possible new directions and an integrated multiscale view that may prove useful in finding solutions for this disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.