Trial reportMedical oncology (Northwood, London, England)2013
Mepilex Lite dressings for managing acute radiation dermatitis in nasopharyngeal carcinoma patients: a systematic controlled clinical trial.
Trial report in Medical oncology (Northwood, London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Mepilex Lite dressing in the management of radiation dermatitis-a systematic review and meta-analysis of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Efficacy and safety of Mepitel film for radiodermatitis: a systematic review and meta-analysis.BMC cancer · 2025Pooled it
- The validity of over-the-counter skin, hair, and nail recommendations for adult patients with cancer: A systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Prevention and treatment of acute radiation-induced skin reactions: a systematic review and meta-analysis of randomized controlled trials.BMC cancer · 2014Pooled it
- What is the appropriate skin cleaning method for nasopharyngeal cancer radiotherapy patients? A randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Trial
- The effect of Mepitel Film on acute radiation-induced skin reactions in head and neck cancer patients: a feasibility study.The British journal of radiology · 2018Trial
- Article
- Systematic review of the tools and outcomes for the assessment of acute radiation dermatitis severity.Clinical and translational radiation oncology · 2025Review
- Photobiomodulation therapy for mitigating severity of radiodermatitis in cancer patients undergoing radiotherapy: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Article
- Prophylactic Use of Mepitel® Film to Prevent Radiation-Induced Moist Desquamation in Cancer Patients.Cureus · 2023Review
- Modern Dressings in Prevention and Therapy of Acute and Chronic Radiation Dermatitis-A Literature Review.Pharmaceutics · 2022Review
- Application of Self-Adhesive Soft Silicone Common Foam Dressing in Reducing Intraoperative Pressure Ulcers in Elderly ICU Patients.Computational and mathematical methods in medicine · 2021Observational
- Review
- Topical treatment of radiation-induced dermatitis: current issues and potential solutions.Drugs in context · 2020Review
- Selection of Appropriate Wound Dressing for Various Wounds.Frontiers in bioengineering and biotechnology · 2020Review
- Airway Management During Anesthetic Induction of Secondary Laryngectomy for Recurrent Laryngeal Cancer: Three Cases of Report and Analysis.Frontiers in medicine · 2018Article
- Radiotherapy in the acute medical setting.Clinical medicine (London, England) · 2015Review
- Protecting the radiation-damaged skin from friction: a mini review.Journal of medical radiation sciences · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
More than 60% nasopharyngeal carcinoma patients receiving the radical radiotherapy treatment will develop moist desquamation skin reaction at some time during the course of treatment. The purpose of this study was to compare the effectiveness of Mepilex Lite dressings and the usual care in the healing of postirradiation dermatitis in nasopharyngeal carcinoma patients. This was a randomized controlled trial, and a sample of 88 nasopharyngeal carcinoma patients who had developed radiation dermatitis was assessed. Comparisons were made regarding parameters related to wound healing, including healing time and wound pain, and also regarding the impact of wound on the patient, including restriction of neck movement, sleep problem, and disturbance in body image. The results showed that radiation-induced dermatitis in the study group (Mepilex Lite, 43 patients) healed in a median of 16 days, which was significantly different from the healing time in the control group (median 23 days, 45 patients; P = 0.009). No statistically significant differences were detected between the 2 groups with respect to neck mobility and appearance disturbance. However, Mepilex significantly improved patients' sleep (P = 0.005). The researchers conclude that Mepilex Lite dressing provides a promising alternative to radiation dermatitis of nasopharyngeal carcinoma patients and is worthy of further research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.