ArticleNucleic acids research1986
Nonepidermal members of the keratin multigene family: cDNA sequences and in situ localization of the mRNAs.
Article in Nucleic acids research, 1986. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia.Journal of anatomy · 2009Review
- Article
- Type II keratins are phosphorylated on a unique motif during stress and mitosis in tissues and cultured cells.Molecular biology of the cell · 2002Article
- Intermediate filament expression in prostate cancer.Cancer metastasis reviews · 1996Review
- A review of intermediate filament biology and their use in pathologic diagnosis.Molecular biology reports · 1994Review
- Structure and site of expression of a murine type II hair keratin.Molecular biology reports · 1992Article
- The SPA2 gene of Saccharomyces cerevisiae is important for pheromone-induced morphogenesis and efficient mating.The Journal of cell biology · 1990Article
- Enhancer elements directing cell-type-specific expression of cytokeratin genes and changes of the epithelial cytoskeleton by transfections of hybrid cytokeratin genes.The EMBO journal · 1989Article
- The intermediate filament system of the keratinizing mouse forestomach epithelium: coexpression of keratins of internal squamous epithelia and of epidermal keratins in differentiating cells.Cell and tissue research · 1988Article
- Localization of keratin mRNA in human tracheobronchial epithelium and bronchogenic carcinomas by in situ hybridization.The American journal of pathology · 1988Article
- Molecular characterization and expression of the stratification-related cytokeratins 4 and 15.The Journal of cell biology · 1988Article
- A group of type I keratin genes on human chromosome 17: characterization and expression.Molecular and cellular biology · 1988Article
- Sequence and expression of a type II keratin, K5, in human epidermal cells.Molecular and cellular biology · 1988Article
- Concerted gene duplications in the two keratin gene families.Journal of molecular evolution · 1988Article
- Differential localization of distinct keratin mRNA-species in mouse tongue epithelium by in situ hybridization with specific cDNA probes.The Journal of cell biology · 1986Article
- Aminoalkylsilane-treated glass slides as support for in situ hybridization of keratin cDNAs to frozen tissue sections under varying fixation and pretreatment conditions.The Histochemical journal · 1986Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A keratin set which consists of a type I 47kd and a type II 57kd protein occurs as a major constituent of the keratin patterns of various internal stratified epithelia of the mouse. We have isolated specific cDNA clones of the two complementary keratin subunits from a cDNA library constructed with polyA+RNA of mouse tongue epithelium and present the complete nucleotide and deduced amino acid sequences of the 57kd protein and about 75% of the corresponding data of the 47kd protein. The comparison of the sequence data with those of known epidermal keratin mRNAs coding for the two types of keratin proteins reveals a fundamentally identical and type-specific organization of the mRNAs into both highly conserved and variable domains. In order to avoid cross-reactions with other members of the keratin multigene family, appropriately taylored 35S-labeled cDNA probes comprising the low and non-homologous 3' coding and noncoding domains of the mRNAs were used for in situ hybridization to tissue sections. The localization and distribution of the corresponding transcripts indicates a strongly compartmentalized keratin expression in mouse tongue epithelium.
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