ArticleMalaria journal2013
Acute respiratory distress syndrome and acute renal failure from Plasmodium ovale infection with fatal outcome.
Article in Malaria journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 5 of them syntheses that pooled it.
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Who cites it
40 citing papers in PubMed, 5 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Comparison of Plasmodium ovale curtisi and Plasmodium ovale wallikeri infections by a meta-analysis approach.Scientific reports · 2021Pooled it
- Severity and mortality of severe Plasmodium ovale infection: A systematic review and meta-analysis.PloS one · 2020Pooled it
- A Systematic Review: Performance of Rapid Diagnostic Tests for the Detection of Plasmodium knowlesi, Plasmodium malariae, and Plasmodium ovale Monoinfections in Human Blood.The Journal of infectious diseases · 2018Pooled it
- Respiratory Complications ofThe American journal of tropical medicine and hygiene · 2017Pooled it
- A systematic review of the clinical presentation, treatment and relapse characteristics of human Plasmodium ovale malaria.Malaria journal · 2017Pooled it
- Prevalence of Plasmodium ovale and Plasmodium malariae Mixed Infections and Associated Mortality in Children with Severe Falciparum Malaria.The American journal of tropical medicine and hygiene · 2026Article
- The hidden malaria: Misidentification of Plasmodium malariae and Plasmodium ovale in low-transmission setting targeted for elimination in Ethiopia.Research square · 2026Article
- Reduction in Asymptomatic falciparum malaria infection amongst schoolchildren in three ecological zones of Ghana between 2017 and 2023.Scientific reports · 2025Article
- Plasmodium ovale Malaria in Travelers and Immigrants to the United States: A Case Series.The American journal of tropical medicine and hygiene · 2025Article
- Lung Damage Induced byACS infectious diseases · 2024Article
- Profile and Determinants for Complications of Imported Malaria in 5 Chinese Provinces From 2014 to 2021: Retrospective Analysis.JMIR public health and surveillance · 2024Article
- A case of severe Plasmodium ovale malaria with acute respiratory distress syndrome and splenic infarction in a male traveller presenting in Italy.Malaria journal · 2024Article
- The kidney-brain pathogenic axis in severe falciparum malaria.Trends in parasitology · 2023Review
- Non-falciparum species and submicroscopic infections in three epidemiological malaria facets in Cameroon.BMC infectious diseases · 2022Article
- Prevalence of non-Plasmodium falciparum species in southern districts of Brazzaville in The Republic of the Congo.Parasites & vectors · 2022Article
- Genetic Diversity and Phylogenetic Relatedness ofMicroorganisms · 2022Article
- Blockade of caspase cascade overcomes malaria-associated acute respiratory distress syndrome in mice.Cell death & disease · 2022Article
- Population genomics in neglected malaria parasites.Frontiers in microbiology · 2022Review
- Neglected malaria parasites in hard-to-reach areas of Odisha, India: implications in elimination programme.Malaria journal · 2021Article
- Epidemiological, Physiological and Diagnostic Comparison ofDiagnostics (Basel, Switzerland) · 2021Review
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlasmodium ovale is one of the causative agents of human malaria. Plasmodium ovale infection has long been thought to be non-fatal. Due to its lower morbidity, P. ovale receives little attention in malaria research.
methodsTwo Malaysians went to Nigeria for two weeks. After returning to Malaysia, they fell sick and were admitted to different hospitals. Plasmodium ovale parasites were identified from blood smears of these patients. The species identification was further confirmed with nested PCR. One of them was successfully treated with no incident of relapse within 12-month medical follow-up. The other patient came down with malaria-induced respiratory complication during the course of treatment. Although parasites were cleared off the circulation, the patient's condition worsened. He succumbed to multiple complications including acute respiratory distress syndrome and acute renal failure.
resultsSequencing of the malaria parasite DNA from both cases, followed by multiple sequence alignment and phylogenetic tree construction suggested that the causative agent for both malaria cases was P. ovale curtisi. DISCUSSION: In this report, the differences between both cases were discussed, and the potential capability of P. ovale in causing severe complications and death as seen in this case report was highlighted.
conclusionPlasmodium ovale is potentially capable of causing severe complications, if not death. Complete travel and clinical history of malaria patient are vital for successful diagnoses and treatment. Monitoring of respiratory and renal function of malaria patients, regardless of the species of malaria parasites involved is crucial during the course of hospital admission.
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