Evidence map›Paper›PMID 24180248›Full record

ArticleJournal of the American Chemical Society2013

Lipid directed intrinsic membrane protein segregation.

Jesper S Hansen, James R Thompson, Claus Hélix-Nielsen, Noah Malmstadt

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Emerging Designs and Applications for Biomembrane Biosensors.Annual review of analytical chemistry (Palo Alto, Calif.) · 2024
    Review
  2. Article
  3. Article
  4. Review
  5. The lipid phase preference of the adenosine AChemical communications (Cambridge, England) · 2019
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Compartmentalization and Transport in Synthetic Vesicles.Frontiers in bioengineering and biotechnology · 2016
    Review
  17. Article
  18. The systematic analysis of protein-lipid interactions comes of age.Nature reviews. Molecular cell biology · 2015
    Review
  19. Glucose transport machinery reconstituted in cell models.Chemical communications (Cambridge, England) · 2015
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jesper S HansenMork Family Department of Chemical Engineering and Materials Science, University of Southern California , 925 Bloom Walk, Los Angeles, California 90089, United States.
James R Thompson
Claus Hélix-Nielsen
Noah Malmstadt

Funding

Connecting plasma membrane function to lipid structure and organization with asymR01GM093279 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MALMSTADT, NOAH · 2010 to 2014
$1.4M
NIGMS NIH HHS R01 GM093279NIGMS NIH HHS R01GM093279
6 · The paper itself

Abstract

We demonstrate a new approach for direct reconstitution of membrane proteins during giant vesicle formation. We show that it is straightforward to create a tissue-like giant vesicle film swelled with membrane protein using aquaporin SoPIP2;1 as an illustration. These vesicles can also be easily harvested for individual study. By controlling the lipid composition we are able to direct the aquaporin into specific immiscible liquid domains in giant vesicles. The oligomeric α-helical protein cosegregates with the cholesterol-poor domains in phase separating ternary mixtures.

Indexed as

LipidsMembrane ProteinsParticle SizeSurface PropertiesLipidsMembrane Proteins

Identifiers

PMID24180248
PMCPMC3886709

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.