ArticleNeuroImage. Clinical2012
Susceptibility-weighted imaging at 7 T: Improved diagnosis of cerebral cavernous malformations and associated developmental venous anomalies.
Article in NeuroImage. Clinical, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 36 citations in OpenAlex.
- Signal and Contrast Optimization With Predicted Excitations (SCOPE) for Accelerating Large FOV Body Imaging at UHF.Magnetic resonance in medicine · 2026Article
- A shielded 32-channel body transceiver array with integrated electronics for 7 T.Magnetic resonance in medicine · 2025Article
- Large Pontine Cavernoma with Hemorrhage: Case Report on Surgical Approach and Recovery.Journal of clinical medicine · 2025Article
- Implementation of a 7T Epilepsy Task Force consensus imaging protocol for routine presurgical epilepsy work-up: effect on diagnostic yield and lesion delineation.Journal of neurology · 2024Article
- Use of a Commercial 7-T MRI Scanner for Clinical Brain Imaging: Indications, Protocols, Challenges, and Solutions-A Single-Center Experience.AJR. American journal of roentgenology · 2023Article
- Symptomatic Developmental Venous Anomaly: State-of-the-Art Review on Genetics, Pathophysiology, and Imaging Approach to Diagnosis.AJNR. American journal of neuroradiology · 2023Review
- SWI by 7T MR Imaging for the Microscopic Imaging Diagnosis of Astrocytic and Oligodendroglial Tumors.AJNR. American journal of neuroradiology · 2022Article
- Improved susceptibility weighted imaging at ultra-high field using bipolar multi-echo acquisition and optimized image processing: CLEAR-SWI.NeuroImage · 2021Article
- Progress in Imaging the Human Torso at the Ultrahigh Fields of 7 and 10.5 T.Magnetic resonance imaging clinics of North America · 2021Review
- Epilepsy Lesion Localization is not Predicted by Developmental Venous Anomaly Location or its FDG-PET Metabolic Activity.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2020Article
- Evolution of UHF Body Imaging in the Human Torso at 7T: Technology, Applications, and Future Directions.Topics in magnetic resonance imaging : TMRI · 2019Review
- Clinical 7 T MRI: Are we there yet? A review about magnetic resonance imaging at ultra-high field.The British journal of radiology · 2019Review
- Key clinical benefits of neuroimaging at 7T.NeuroImage · 2018Review
- Neuroimaging of Cavernous Malformations.Current pain and headache reports · 2017Review
- Sensitivity of susceptibility-weighted imaging in detecting developmental venous anomalies and associated cavernomas and microhemorrhages in children.Neuroradiology · 2017Article
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimIn the diagnosis of cerebral cavernous malformations (CCMs) magnetic resonance imaging is established as the gold standard. Conventional MRI techniques have their drawbacks in the diagnosis of CCMs and associated venous malformations (DVAs). The aim of our study was to evaluate susceptibility weighted imaging SWI for the detection of CCM and associated DVAs at 7 T in comparison with 3 T. PATIENTS AND
methods24 patients (14 female, 10 male; median age: 38.3 y (21.1 y-69.1 y) were included in the study. Patients enrolled in the study received a 3 T and a 7 T MRI on the same day. The following sequences were applied on both field strengths: a T1 weighted 3D GRE sequence (MP-RAGE) and a SWI sequence. After obtaining the study MRIs, eleven patients underwent surgery and 13 patients were followed conservatively or were treated radio-surgically.
resultsPatients initially presented with haemorrhage (n = 4, 16.7%), seizures (n = 2, 8.3%) or other neurology (n = 18, 75.0%). For surgical resected lesions histopathological findings verified the diagnosis of CCMs. A significantly higher number of CCMs was diagnosed at 7 T SWI sequences compared with 3 T SWI (p < 0.05). Additionally diagnosed lesions on 7 T MRI were significantly smaller compared to the initial lesions on 3 T MRIs (p < 0.001). Further, more associated DVAs were diagnosed at 7 T MRI compared to 3 T MRI.
conclusionSWI sequences at ultra-high-field MRI improve the diagnosis of CCMs and associated DVAs and therefore add important pre-operative information.
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