Evidence map›Paper›PMID 24179707›Full record

ArticleOncoimmunology2013

Biological insights into BRAF

Giuseppina Improta, Giuseppe Pelosi, Elena Tamborini, Marco Donia, Mario Santinami, Filippo de Braud, Filippo Fraggetta

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03447678 (Phase II Study to Test Pembrolizumab), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03447678 phase2unknown statusnot on this mapstarted 2018, after this paper: background citation

Phase II Study to Test Pembrolizumab (MK-3475) in First Line Treatment of Advanced NSCLC Patients With PD-L1 Low Tumors (<50%)_ PEOPLE TRIAL (Pembrolizumab in Pd-L1 Low Expressors).

TypeinterventionalSponsorFondazione IRCCS Istituto Nazionale dei Tumori, MilanoRan2018 to 2022Enrolled65ConditionsNon Small Cell Lung Cancer (NSCLC)ArmsPembrolizumab
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 4 countries.

Giuseppina ImprotaLaboratory of Clinical Research and Molecular Diagnostics; IRCCS - CROB Centro di Riferimento Oncologico della Basilicata; Rionero in Vulture (Pz), Italy.
Giuseppe Pelosi
Elena Tamborini
Marco Donia
Mario Santinami
Filippo de Braud
Filippo Fraggetta
Fondazione IRCCS Istituto Nazionale dei Tumori · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto Nazionale di Fisica Nucleare, Sezione di Milano · ITOspedale Cannizzaro · ITUniversity of Catania · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some experimental evidence indicates that uncommon

Indexed as

BRAFhomozygosisimmunotherapymelanomaMHCvemurafenib

Identifiers

PMID24179707
PMCPMC3812198
OpenAlexW2034210528

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.