Evidence map›Paper›PMID 24179546›Full record

ArticleOncology letters2013

A single nucleotide polymorphism in EZH2 predicts overall survival rate in patients with cholangiocarcinoma.

Elisa Paolicchi, Paola Pacetti, Elisa Giovannetti, Andrea Mambrini, Massimo Orlandi, Francesco Crea, Antonello A Romani, Roberta Tartarini, Romano Danesi, Godefridus J Peters and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Prognostic Significance ofCancer genomics & proteomics · 2025
    Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Correlations ofBioscience reports · 2018
    Article
  7. Article
  8. Review
  9. Article
  10. Predictive and prognostic molecular markers for cholangiocarcinoma in Han Chinese population.International journal of clinical and experimental medicine · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Elisa PaolicchiDepartment of Internal Medicine, Division of Pharmacology, University of Pisa, Pisa I-56126, Italy.
Paola Pacetti
Elisa Giovannetti
Andrea Mambrini
Massimo Orlandi
Francesco Crea
Antonello A Romani
Roberta Tartarini
Romano Danesi
Godefridus J Peters
Maurizio Cantore
Accademia di Belle Arti di Carrara · ITUniversity of Pisa · ITAmsterdam UMC Location VUmc · NLUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholangiocarcinoma (CCA) is a deadly disease arising from the malignant transformation of cholangiocytes. Enhancer of zeste homolog 2 (EZH2) is overexpressed in poorly differentiated CCA. Functional single nucleotide polymorphisms (SNPs) in this gene may affect the role of EZH2 in cholangiocarcinogenesis and chemoresistance. The aim of the current study was to evaluate the correlation between EZH2 SNPs and clinical outcome. Using PROMO3.0, GeneCard and MicroSNiper, 4 EZH2 SNPs with functional relevance in CCA were selected

Indexed as

cholangiocarcinomaECX regimenEZH2polycombpolymorphism

Identifiers

PMID24179546
PMCPMC3813671
OpenAlexW2114063363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.