ArticleCurrent neuropharmacology2013
Neurobiological consequences of sleep deprivation.
Article in Current neuropharmacology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- Suicidality in adults with obstructive sleep apnea: A systematic review and Meta-Analysis.Sleep & breathing = Schlaf & Atmung · 2025Pooled it
- Early Life Sleep Deprivation and Brain Development: Insights From Human and Animal Studies.Frontiers in neuroscience · 2022Pooled it
- Effects of experimental sleep deprivation on aggressive, sexual and maternal behaviour in animals: a systematic review protocol.BMJ open science · 2018Pooled it
- Feedback Blunting: Total Sleep Deprivation Impairs Decision Making that Requires Updating Based on Feedback.Sleep · 2015Trial
- Chronic REM Sleep Deprivation Induces Metabolic and Neurotoxic Alterations Associated with Affective and Cognitive Deficit in Male Wistar Rats: Involvement of HPA Axis, Cholinergic, Inflammatory, and Oxidative Stress Pathways.Neurochemical research · 2026Article
- Sleep deprivation and memory: A neurobiological perspective.IBRO neuroscience reports · 2026Article
- Exploring β-caryophyllene: a non-psychotropic cannabinoid's potential in mitigating cognitive impairment induced by sleep deprivation.Archives of pharmacal research · 2025Review
- Sleep deprivation induces late deleterious effects in a pharmacological model of Parkinsonism.Experimental brain research · 2024Article
- Association Between Sleep-related Cognitions, Sleep-related Behaviors, and Insomnia in Patients with Anxiety and Depression: A Cross-sectional Study.Indian journal of psychological medicine · 2024Article
- Transcranial Irradiation Mitigates Paradoxical Sleep Deprivation Effect in an Age-Dependent Manner: Role of BDNF and GLP-1.Neurochemical research · 2024Article
- Editorial: The 3 S's: sex, stress, and sleep as risk factors for dementias.Frontiers in aging neuroscience · 2024Article
- Actigraphy Analysis of Sleep Associates with Salivary IL-6 Concentration in Institutionalized Older Individuals.Diseases (Basel, Switzerland) · 2023Article
- Total Sleep Deprivation Increases Brain Age Prediction Reversibly in Multisite Samples of Young Healthy Adults.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Myricetin prevents sleep deprivation-induced cognitive impairment and neuroinflammation in rat brainThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2022Article
- Volumetric differences in hippocampal subfields and associations with clinical measures in myalgic encephalomyelitis/chronic fatigue syndrome.Journal of neuroscience research · 2022Article
- Sodium valproate improves sensorimotor gating deficit induced by sleep deprivation at low dosesTurkish journal of medical sciences · 2021Article
- Animal cognition in an urbanised world.Frontiers in ecology and evolution · 2021Article
- The Moderating Effect of Physical Activity on the Relationship between Sleep and Emotional Distress and the Difference between Blacks and Whites: A Secondary Data Analysis Using the National Health Interview Survey from 2005-2015.International journal of environmental research and public health · 2021Article
- Effect of the cPKCγ-Ng Signaling System on Rapid Eye Movement Sleep Deprivation-Induced Learning and Memory Impairment in Rats.Frontiers in psychiatry · 2021Article
- Understanding stress: Insights from rodent models.Current research in neurobiology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Although the physiological function of sleep is not completely understood, it is well documented that it contributes significantly to the process of learning and memory. Ample evidence suggests that adequate sleep is essential for fostering connections among neuronal networks for memory consolidation in the hippocampus. Sleep deprivation studies are extremely valuable in understanding why we sleep and what are the consequences of sleep loss. Experimental sleep deprivation in animals allows us to gain insight into the mechanism of sleep at levels not possible to study in human subjects. Many useful approaches have been utilized to evaluate the effect of sleep loss on cognitive function, each with relative advantages and disadvantages. In this review we discuss sleep and the detrimental effects of sleep deprivation mostly in experimental animals. The negative effects of sleep deprivation on various aspects of brain function including learning and memory, synaptic plasticity and the state of cognition-related signaling molecules are discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.