ReviewClinical Medicine Insights. Oncology2013
Spinal osteosarcoma.
Review in Clinical Medicine Insights. Oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Clinical effectiveness of Enneking appropriate versus Enneking inappropriate procedure in patients with primary osteosarcoma of the spine: a systematic review with meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2020Pooled it
- Primary spinal bone sarcomas in Japan: a nationwide comparative analysis of demographic and pathologic features, treatment patterns, and survival.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Review
- Preoperative Multi-model Images-based Radiomics Model for Distinguishing Spinal Osteosarcoma and Chondrosarcoma.Current medical imaging · 2025Article
- En bloc resection, including the cord for tumor-free margin, in a multilevel osteosarcoma of the spine: 20-year disease-free survival. Illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Anlotinib combined with penpulimab in the treatment of advanced adult thoracic spinal osteosarcoma: a case report.Frontiers in pharmacology · 2025Article
- Spinal lesions: a comprehensive radiologic overview.Frontiers in radiology · 2025Review
- Exploring Pediatric Vertebral, Sacral, and Pelvic Osteosarcomas through the NCDB: Demographics, Treatment Utilization, and Survival Outcomes.Children (Basel, Switzerland) · 2024Article
- Tumors of the Posterior Elements of the Spine in Children-an Overview.Indian journal of surgical oncology · 2024Review
- Malignant Brain and Spinal Tumors Originating from Bone or Cartilage.Advances in experimental medicine and biology · 2023Article
- Prognostic factors and treatment outcomes of spinal osteosarcoma: Surveillance, epidemiology, and end results database analysis.Frontiers in oncology · 2023Article
- Spinal giant cell-rich osteosarcoma-diagnostic dilemma and treatment strategy: A case report.World journal of clinical cases · 2022Article
- Paraplegia Caused by Multifocal Osteosarcoma With Spinal Lesions.International journal of spine surgery · 2021Article
- The role of percutaneous transarterial embolization in the management of spinal bone tumors: a literature review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021Review
- An overview of the tumors affecting the spine-inside to out.Neuro-oncology practice · 2020Article
- Economics of the Management of Craniospinal Chordoma and Chondrosarcoma and the feasibility of the bundled payment model.BMC neurology · 2020Article
- Bone up on spinal osseous lesions: a case review series.Insights into imaging · 2020Review
- Long noncoding RNA BSN-AS2 induced by E2F1 promotes spinal osteosarcoma progression by targeting miR-654-3p/SYTL2 axis.Cancer cell international · 2020Article
- MicroRNA-493-5p inhibits proliferation and metastasis of osteosarcoma cells by targeting Kruppel-like factor 5.Journal of cellular physiology · 2019Article
- Bone transport using the Ilizarov method for osteosarcoma patients with tumor resection and neoadjuvant chemotherapy.Journal of bone oncology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although osteosarcoma represents the second most common primary bone tumor, spinal involvement is rare, accounting for 3%-5% of all osteosarcomas. The most frequent symptom of osteosarcoma is pain, which appears in almost all patients, whereas more than 70% exhibit neurologic deficit. At a molecular level, it is a tumor of great genetic complexity and several genetic disorders have been associated with its appearance. Early diagnosis and careful surgical staging are the most important factors in accomplishing sufficient management. Even though overall prognosis remains poor, en-block tumor removal combined with adjuvant radiotherapy and chemotherapy is currently the treatment of choice. This paper outlines histopathological classification, epidemiology, diagnostic procedures, and current concepts of management of spinal osteosarcoma.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.