ArticleBiomarkers in cancer2013
Use of Ber-EP4 and Epithelial Specific Antigen to Differentiate Clinical Simulators of Basal Cell Carcinoma.
Article in Biomarkers in cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 41 citations in OpenAlex.
- Extremely Rare Pulmonary Metastases of Skin Basal Cell Carcinoma: Report of Two Cases with Clinicopathological Features.Biomedicines · 2023Article
- Ber-EP4 staining patterns on basal cell carcinomas.Northern clinics of Istanbul · 2023Article
- Differences in actin expression between primary and recurrent facial basal cell carcinomas as a prognostic factor of local recurrence.Postepy dermatologii i alergologii · 2021Article
- Endoscopic features and associated histology of an basaloid squamous cell carcinoma of the esophagus at the very early stage.BMC cancer · 2019Article
- Applications of SNAP-tag technology in skin cancer therapy.Health science reports · 2019Review
- Basal Cell Carcinoma Arises from Interfollicular Layer of Epidermis.Journal of oncology · 2018Article
- Cutaneous Basal Cell Carcinoma with Lymph Node and Pulmonary Metastases.Case reports in oncological medicine · 2018Article
- Automated selection of aptamers against cholangiocarcinoma cells on an integrated microfluidic platform.Biomicrofluidics · 2017Article
- Implementation of fluorescence confocal mosaicking microscopy by "early adopter" Mohs surgeons and dermatologists: recent progress.Journal of biomedical optics · 2017Article
- The Use of BEREP4 Immunohistochemistry Staining for Detection of Basal Cell Carcinoma.Journal of skin cancer · 2017Review
- The importance of cytokeratin 19 expression in the differentiation of Basal cell carcinoma and trichoepithelioma.Journal of clinical and diagnostic research : JCDR · 2015Article
- Multiscale BerEp4 molecular imaging of microtumor phantoms: toward theranostics for basal cell carcinoma.Molecular imaging · 2014Article
- Adhesion Molecules in Non-melanoma Skin Cancers: A Comprehensive Review.In vivo (Athens, Greece)Review
- Expression of BerEP4 and CD10 IHC Markers in Basal Cell Carcinoma, Squamous Cell Carcinoma and Adnexal Tumours of Follicular Differentiation: A Comparative Study.Indian journal of dermatologyArticle
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
EpCam is a transmembrane epithelial adhesion molecule present on all non-squamous epithelial cells. It is often overexpressed in certain carcinomas, such as breast and colon, and in dermatology, eg, basal cell carcinoma (BCC). Various monoclonal antibodies have been used to detect EpCam, including BerEP4 and epithelial specific antigen. We compared anti-EpCam clones, BerEP4, and epithelial specific antigen clone VU-1D9. One hundred and twelve lesions were stained with both antibodies. All basal cell carcinomas stained uniformly and strongly positive with both antibodies. Diffuse positive staining was also seen in all trichoepitheliomas and merkel cell carcinomas. Focal positive staining was seen in squamous cell carcinoma and benign sebaceous neoplasms. Clone VU-1D9 was more likely to produce focal positive staining as compared to BerEP4. This focal positive staining of sebaceous neoplasms and squamous cell carcinomas is a potential diagnostic pitfall.
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