Evidence map›Paper›PMID 24177413›Full record

Trial reportContemporary clinical trials2014

Rationale, design, and baseline characteristics of a community-based comparative effectiveness trial to prevent type 2 diabetes in economically disadvantaged adults: the RAPID Study.

Ronald T Ackermann, Emily A Finch, Karen K Schmidt, Helena M Hoen, Laura M Hays, David G Marrero, Chandan Saha

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Contemporary clinical trials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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  3. PREVENT-DM Comparative Effectiveness Trial of Lifestyle Intervention and Metformin.American journal of preventive medicine · 2017 · on this map
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ronald T AckermannDepartment of Medicine, Northwestern University Feinberg School of Medicine, 750 N. Lake Shore Dr., 10th Floor, Chicago, IL 60611, United States. Electronic address: r.ackermann@northwestern.edu.
Emily A FinchDepartment of Medicine, Northwestern University Feinberg School of Medicine, 750 N. Lake Shore Dr., 10th Floor, Chicago, IL 60611, United States.
Karen K SchmidtDepartment of Medicine, Indiana University School of Medicine, 410 W 10th St, Suite 3000, Indianapolis, IN 46202, United States.
Helena M HoenDepartment of Biostatistics, Indiana University School of Medicine, 410 W 10th St, Suite 3000, Indianapolis, IN 46202, United States.
Laura M HaysIndiana University School of Nursing, Indianapolis, 1111 Middle Dr., Indianapolis, IN 46202, United States.
David G MarreroDepartment of Medicine, Indiana University School of Medicine, 410 W 10th St, Suite 3000, Indianapolis, IN 46202, United States.
Chandan SahaDepartment of Biostatistics, Indiana University School of Medicine, 410 W 10th St, Suite 3000, Indianapolis, IN 46202, United States.
Indiana University – Purdue University Indianapolis · USNorthwestern University · USIndiana University School of Medicine

Funding

Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
MULTIDISCIPLINARY CLINICAL AND TRANSLATIONAL SCIENCE (MCTS) PROGRAM (UL1)UL1RR025741 · NCRR · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GREENLAND, PHILIP · 2008 to 2011
$24.7M
Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
Primary Care-Community Partnerships to Prevent DiabetesR18DK079855 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ACKERMANN, RONALD T. · 2007 to 2011
$2.8M
NCATS NIH HHS UL1 TR001108NCRR NIH HHS UL1 RR025741NCRR NIH HHS UL1RR025741NIDDK NIH HHS R18 DK079855NIDDK NIH HHS R18DK079855
6 · The paper itself

Abstract

Reaching Out and Preventing Increases in Diabetes (RAPID) is a community-based randomized trial evaluating the comparative costs and effectiveness of a group-based adaption of the DPP lifestyle intervention developed and implemented in partnership with the YMCA. RAPID enrolled adult primary care patients, with BMI 24 kg/m(2) or higher and abnormal glucose metabolism (HbA1c 5.7-6.9% or fasting plasma glucose 100-125 mg/dL). 509 participants were enrolled and randomized to one of two groups: standard clinical advice plus free-of-charge access to a group-based adaption of the DPP offered by the Y, versus standard clinical advice alone. Key outcomes for future analysis will include differences in body weight and other cardiovascular risk factors over a 24-month intervention period. At baseline, RAPID participants had a mean (SD) age of 51 ± 12.1 years, weight of 225.1 ± 56.2 lbs, and BMI of 36.9 ± 8.6 kg/m(2). 70.7% were women, 57.2% were African American, 35.4% were non-Hispanic White, and 3.2% were Hispanic. Mean HbA1c was 6.05 ± 0.34%. Additionally, 55.4% of participants had a baseline systolic blood pressure of ≥130 mmHg, 33.1% had a total blood cholesterol exceeding 200mg/dL, and 74% reported a household income of <$25,000. The RAPID Study successfully randomized a large cohort of participants with a wide distribution of age, body weight, and race who are at high risk for developing type 2 diabetes.

Indexed as

Exercise TherapyPovertyRisk Reduction BehaviorWeight Reduction ProgramsAdultComparative Effectiveness ResearchCounselingDiabetes Mellitus, Type 2FemaleHealth Services AccessibilityHumansMaleMiddle AgedObesityOverweightCommunity researchLifestyle interventionOverweight/obesityPre-diabetesPrimary preventionType 2 diabetes mellitus

Identifiers

PMID24177413
PMCPMC4373538
OpenAlexW2094944042

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.