GuidelineJournal of the American Dental Association (1939)2013
Topical fluoride for caries prevention: executive summary of the updated clinical recommendations and supporting systematic review.
Guideline in Journal of the American Dental Association (1939), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 131 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Light Curable Resin Modified Glass Ionomer Varnish on Inhibiting the Progression of Non-Cavitated Proximal Carious Lesions: A Randomized Controlled Trial
Efficacy of Fluor Protector S in the Prevention of Tooth Decay in Adolescents
Who cites it
131 citing papers in PubMed, 8 syntheses or guidelines pooled it, 345 citations in OpenAlex.
- Effectiveness of School Fluoride Delivery Programs: A Community Guide Systematic Review.American journal of preventive medicine · 2025Pooled it
- Assessment of the Quality of Current American Dental Association Clinical Practice Guidelines.JDR clinical and translational research · 2023Pooled it
- The additional benefit of professional fluoride application for children as an adjunct to regular fluoride toothpaste: a systematic review and meta-analysis.Clinical oral investigations · 2021Pooled it
- Silver diamine fluoride for managing carious lesions: an umbrella review.BMC oral health · 2019Pooled it
- A systematic review of decision analytic modeling techniques for the economic evaluation of dental caries interventions.PloS one · 2019Pooled it
- Dental caries prevention in children and adolescents: a systematic quality assessment of clinical practice guidelines.Clinical oral investigations · 2018Pooled it
- One-to-one oral hygiene advice provided in a dental setting for oral health.The Cochrane database of systematic reviews · 2018Pooled it
- Fluoride mouthrinses for preventing dental caries in children and adolescents.The Cochrane database of systematic reviews · 2016Pooled it
- Concentration of Fluoride in Saliva After Fluoride Gel Application: A Randomised Clinical Trial.International dental journal · 2024Trial
- Cost-effectiveness and cost-benefit analyses of fluoride varnish for caries prevention in Guangxi, China.BMC oral health · 2024Trial
- Effect of Silver Diamine Fluoride on Caries Arrest and Prevention: The CariedAway School-Based Randomized Clinical Trial.JAMA network open · 2023Trial
- Is Silver Diamine Fluoride Effective in Arresting Enamel Caries? A Randomized Clinical Trial.International journal of environmental research and public health · 2022Trial
- Efficacy evaluation of an anti-caries varnish: protocol for a phase II randomised controlled trial.BMJ open · 2017Trial
- Effect of a chlorhexidine/thymol and a fluoride varnish on caries development in erupting permanent molars: a comparative study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2015Trial
- Efficacy of fluoride varnish and casein phosphopeptide-amorphous calcium phosphate for remineralization of primary teeth: a randomized clinical trial.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2015Trial
- Preventing caries in preschoolers: successful initiation of an innovative community-based clinical trial in Navajo Nation Head Start.Contemporary clinical trials · 2014Trial
- Age-Stratified Association Between CPI Screening Categories and Caries Experience in the Permanent Dentition of Children and Adolescents from Southwest Romania: A Multicenter Cross-Sectional Clinical Study.Children (Basel, Switzerland) · 2026Article
- Article
- Probiotic Bifidobacterium animalis subsp. lactis BL-11 attenuates dental caries development in a Streptococcus mutans-induced rat model.Odontology · 2026Article
- Dental Caries in Older Adults: A Narrative Review for Non-Dental Providers.International journal of environmental research and public health · 2026Review
71 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issuedDosage error in article text
Authors and funding
18 authors at 9 institutions in 1 country.
Funding
Abstract
backgroundA panel of experts convened by the American Dental Association (ADA) Council on Scientific Affairs presents evidence-based clinical recommendations regarding professionally applied and prescription-strength, home-use topical fluoride agents for caries prevention. These recommendations are an update of the 2006 ADA recommendations regarding professionally applied topical fluoride and were developed by using a new process that includes conducting a systematic review of primary studies. TYPES OF STUDIES REVIEWED: The authors conducted a search of MEDLINE and the Cochrane Library for clinical trials of professionally applied and prescription-strength topical fluoride agents--including mouthrinses, varnishes, gels, foams and pastes--with caries increment outcomes published in English through October 2012.
resultsThe panel included 71 trials from 82 articles in its review and assessed the efficacy of various topical fluoride caries-preventive agents. The panel makes recommendations for further research. PRACTICAL IMPLICATIONS: The panel recommends the following for people at risk of developing dental caries: 2.26 percent fluoride varnish or 1.23 percent fluoride (acidulated phosphate fluoride) gel, or a prescription-strength, home-use 0.05 percent fluoride gel or paste or 0.09 percent fluoride mouthrinse for patients 6 years or older. Only 2.26 percent fluoride varnish is recommended for children younger than 6 years. The strengths of the recommendations for the recommended products varied from "in favor" to "expert opinion for." As part of the evidence-based approach to care, these clinical recommendations should be integrated with the practitioner's professional judgment and the patient's needs and preferences.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.