Evidence map›Paper›PMID 24175293›Full record

Trial reportBioMed research international2013

In vitro and in vivo survival and colonic adhesion of Pediococcus acidilactici MTCC5101 in human gut.

Praveen P Balgir, Baljinder Kaur, Tejinder Kaur, Natisha Daroch, Gurpreet Kaur

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Dietary ProbioticNutrients · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Antidiabetic Effects ofNutrients · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Genomic Insight intoMicroorganisms · 2020
    Article
  14. Article
  15. Construction of a shuttle expression vector for lactic acid bacteria.Journal, genetic engineering & biotechnology · 2019
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Praveen P BalgirDepartment of Biotechnology, Punjabi University, Punjab, Patiala 147 002, India.
Baljinder Kaur
Tejinder Kaur
Natisha Daroch
Gurpreet Kaur
Punjabi University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aims to investigate the probiotic nature of Pediococcus acidilactici MTCC5101 by an in vitro assay of bacterial adherence to intestinal epithelial cells of human gastrointestinal (GI) tract using Caco-2 cell line. Further to assess the in vivo survival in the GI tract, oral feeding was carried out with the help of 10 healthy volunteers. The effect on wellness was assessed by studying blood biochemical parameters of the volunteers. The survival of the bacteria was assessed using PCR-based detection of P. acidilactici MTCC5101 in fecal samples. The probiotic nature of P. acidilactici MTCC 5101 was strengthened by its adherence to the intestinal epithelial Caco-2 cell line in the in vitro SEM observations. Oral feeding study for assessing the survival of bacteria in GI tract of volunteers showed the strain to be established in the GI tract which survived for about 2 weeks after feeding.

Indexed as

Microbial ViabilityProbioticsBacterial AdhesionCaco-2 CellsEnterocytesFemaleHumansIntestinal MucosaMalePediococcusTime Factors

Identifiers

PMID24175293
PMCPMC3794518
OpenAlexW2090710893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.