ReviewJRSM cardiovascular disease2012
Assessment of leukocyte trafficking in humans using the cantharidin blister model.
Review in JRSM cardiovascular disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- The translational potential of inflammation-induced skin blister human models in exploring the pathogenesis of periodontitis and its systemic health implications.Frontiers in immunology · 2024Review
- Atherosclerosis is a major human killer and non-resolving inflammation is a prime suspect.Cardiovascular research · 2021Review
- Blocking elevated p38 MAPK restores efferocytosis and inflammatory resolution in the elderly.Nature immunology · 2020Article
- Boosting Inflammation Resolution in Atherosclerosis: The Next Frontier for Therapy.The American journal of pathology · 2017Review
- Resolution of inflammation: a new therapeutic frontier.Nature reviews. Drug discovery · 2016Review
- Novel translational model of resolving inflammation triggered by UV-killed E. coli.The journal of pathology. Clinical research · 2016Article
- Characterisation of leukocytes in a human skin blister model of acute inflammation and resolution.PloS one · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cantharidin blister model provides an in vivo assessment of the innate inflammatory response in humans. It allows researchers to profile the acute and resolving inflammatory response in healthy and diseased states and for the design of crossover trials for the testing of new treatments for acute inflammation. Below we describe the materials and methods required to prepare, induce, aspirate and analyse the forearm cantharidin blisters, in preparation for future study design.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.