Evidence map›Paper›PMID 24174899›Full record

ReviewDialogues in clinical neuroscience2013

Animal models and high field imaging and spectroscopy.

Gülin Öz, Ivan Tkáč, Kamil Uğurbil

Abstract readReview
In one paragraph

Review in Dialogues in clinical neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Increases in BrainFrontiers in physiology · 2017
    Article
  5. Fat-water MRI of a diet-induced obesity mouse model at 15.2T.Journal of medical imaging (Bellingham, Wash.) · 2016
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gülin ÖzCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, USA.
Ivan Tkáč
Kamil Uğurbil

Funding

ZOOMED FUNCT IMAGING IN HUMAN BRAIN AT 7T W/ SIMULT HIGH SPATIAL &TEMPORAL RESP41RR008079 · NCRR · UNIVERSITY OF MINNESOTA TWIN CITIES · PI UGURBIL, KAMIL · 1993 to 2011
$16.3M
NMR Imaging and SpectroscopyP41EB015894 · NIBIB · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2017
$8.4M
Institutional Center Cores for Advanced NeuroimagingP30NS076408 · NINDS · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2020
$4.2M
Magnetic Resonance Spectroscopy Biomarkers of NeurodegenerationR01NS070815 · NINDS · UNIVERSITY OF MINNESOTA · PI OZ, GULIN · 2010 to 2014
$1.6M
NCRR NIH HHS P41 RR008079NIBIB NIH HHS P41 EB015894NINDS NIH HHS P30 NS076408NINDS NIH HHS R01 NS070815
6 · The paper itself

Abstract

A plethora of magnetic resonance (MR) techniques developed in the last two decades provide unique and noninvasive measurement capabilities for studies of basic brain function and brain diseases in humans. Animal model experiments have been an indispensible part of this development. MR imaging and spectroscopy measurements have been employed in animal models, either by themselves or in combination with complementary and often invasive techniques, to enlighten us about the information content of such MR methods and/or verify observations made in the human brain. They have also been employed, with or independently of human efforts, to examine mechanisms underlying pathological developments in the brain, exploiting the wealth of animal models available for such studies. In this endeavor, the desire to push for ever-higher spatial and/or spectral resolution, better signal-to-noise ratio, and unique image contrast has inevitably led to the introduction of increasingly higher magnetic fields. As a result, today, animal model studies are starting to be conducted at magnetic fields ranging from ~ 11 to 17 Tesla, significantly enhancing the armamentarium of tools available for the probing brain function and brain pathologies.

Indexed as

Models, AnimalAnimalsBrainBrain DiseasesHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopySpecies Specificitybrain functionfunctional imagingneurometabolismspectroscopy

Identifiers

PMID24174899
PMCPMC3811099

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.