ArticleJournal of neurophysiology2014
Differential contributions of basal ganglia and thalamus to song initiation, tempo, and structure.
Article in Journal of neurophysiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 23 citations in OpenAlex.
- High-throughput assessment of vocal modulation following chemogenetic inhibition in songbirds.iScience · 2026Article
- Differential morphology and distribution of GFAP astrocytes in vocal brain circuit in a songbird Southern house wren and humans.Frontiers in neuroanatomy · 2026Article
- Introductory notes before zebra finch song have unique timing properties while sharing acoustic properties with song.bioRxiv : the preprint server for biology · 2025Article
- Variable and slow-paced neural dynamics in HVC underlie plastic song production in juvenile zebra finches.BMC neuroscience · 2024Article
- Tracing the development of learned song preferences in the female zebra finch brain with functional magnetic resonance imaging.Developmental neurobiology · 2024Article
- What Is the Role of Thalamostriatal Circuits in Learning Vocal Sequences?Frontiers in neural circuits · 2021Article
- Vocal learning in songbirds requires cholinergic signaling in a motor cortex-like nucleus.Journal of neurophysiology · 2018Article
- Origins of basal ganglia output signals in singing juvenile birds.Journal of neurophysiology · 2015Article
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3 authors at 1 institution in 1 country.
Funding
Abstract
Basal ganglia-thalamocortical circuits are multistage loops critical to motor behavior, but the contributions of individual components to overall circuit function remain unclear. We addressed these issues in a songbird basal ganglia-thalamocortical circuit (the anterior forebrain pathway, AFP) specialized for singing and critical for vocal plasticity. The major known afferent to the AFP is the premotor cortical nucleus, HVC. Surprisingly, previous studies found that lesions of HVC alter song but do not eliminate the ability of the AFP to drive song production. We therefore used this AFP-driven song to investigate the role of basal ganglia and thalamus in vocal structure, tempo, and initiation. We found that lesions of the striatopallidal component (Area X) slowed song and simplified its acoustic structure. Elimination of the thalamic component (DLM) further simplified the acoustic structure of song and regularized its rhythm but also dramatically reduced song production. The acoustic structure changes imply that sequential stages of the AFP each add complexity to song, but the effects of DLM lesions on song initiation suggest that thalamus is a locus of additional inputs important to initiation. Together, our results highlight the cumulative contribution of stages of a basal ganglia-thalamocortical circuit to motor output along with distinct involvement of thalamus in song initiation or "gating."
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