ReviewCurrent pain and headache reports2013
Altitude headache.
Review in Current pain and headache reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Efficacy of ibuprofen on prevention of high altitude headache: A systematic review and meta-analysis.PloS one · 2017Pooled it
- Early adaptation to high-altitude: Mood and cognitive responses at simulated 4500 m.Physiological reports · 2025Article
- Parietal-specific activation reveals pain from inadequate levels of altitude acclimatization/ adaptation.PloS one · 2025Article
- Rapid altitude displacement induce zebrafish appearing acute high altitude illness symptoms.Heliyon · 2024Article
- Does Lake Louise questionnaire interpret high-altitude headache as acute mountain sickness? Experience in the western Himalayas.The Indian journal of medical research · 2024Article
- Using machine learning to determine the correlation between physiological and environmental parameters and the induction of acute mountain sickness.BMC bioinformatics · 2022Article
- Thickened Retinal Nerve Fiber Layers Associated With High-Altitude Headache.Frontiers in physiology · 2022Article
- Association ofBioMed research international · 2020Article
- Plasma proteomic study of acute mountain sickness susceptible and resistant individuals.Scientific reports · 2018Article
- Obesity as a Conditioning Factor for High-Altitude Diseases.Obesity facts · 2017Review
- IL-10 Dysregulation in Acute Mountain Sickness Revealed by Transcriptome Analysis.Frontiers in immunology · 2017Article
- Acute mountain sickness among tourists visiting the high-altitude city of Lhasa at 3658 m above sea level: a cross-sectional study.Archives of public health = Archives belges de sante publique · 2016Article
- Wilderness medicine at high altitude: recent developments in the field.Open access journal of sports medicine · 2015Review
- Pseudo-subarachnoid haemorrhage due to chronic hypoxaemia: case report and review of the literature.BMC neurology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High altitude headache (HAH) has been defined by the International Headache Society as a headache that appears within 24 hours after ascent to 2,500 m or higher [1••]. The headache can appear in isolation or as part of acute mountain sickness (AMS), which has more dramatic symptoms than the headache alone. If symptoms are ignored, more serious conditions such as high altitude cerebral edema (HACE), high altitude pulmonary edema (HAPE), or even death may ensue. While there is no definitive understanding of the underlying pathophysiologic mechanism, it is speculated that HAH occurs from the combination of hypoxemia-induced intracranial vasodilation and subsequent cerebral edema. There are a number of preventive measures that can be adopted prior to ascending, including acclimatization and various medications. A variety of pharmacological interventions are also available to clinicians to treat this extremely widespread condition.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.