ArticleKidney international2013
A crystal-clear mechanism of chronic kidney disease.
Article in Kidney international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 34 citations in OpenAlex.
- Hyperuricemia in Chronic Kidney Disease: Emerging Pathophysiology and a Novel Therapeutic Strategy.International journal of molecular sciences · 2025Review
- Tartronic Acid as a Potential Inhibitor of Pathological Calcium Oxalate Crystallization.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Machine learning-based comparison of factors influencing estimated glomerular filtration rate in Chinese women with or without non-alcoholic fatty liver.World journal of clinical cases · 2024Article
- Can uric acid blood levels in renal transplant recipients predict allograft outcome?Renal failure · 2021Article
- Hyperuricemia and hypertriglyceridemia indicate tubular atrophy/interstitial fibrosis in patients with IgA nephropathy and membranous nephropathy.International urology and nephrology · 2021Article
- Parathyroidectomy slows renal function decline in patients with primary hyperparathyroidism.Journal of endocrinological investigation · 2021Article
- Uric Acid and the Risks of Kidney Failure and Death in Individuals With CKD.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2018Observational
- An update on the role of the inflammasomes in the pathogenesis of kidney diseases.Pediatric nephrology (Berlin, Germany) · 2016Review
- Characterization and Activation of NLRP3 Inflammasomes in the Renal Medulla in Mice.Kidney & blood pressure research · 2016Article
- Nephropathy in dietary hyperoxaluria: A potentially preventable acute or chronic kidney disease.World journal of nephrology · 2014Review
- Pattern recognition receptors and the inflammasome in kidney disease.Nature reviews. Nephrology · 2014Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Knauf et al. demonstrate that prolonged activation of the intrarenal inflammasome is responsible for the loss of kidney function in oxalate crystal nephropathy. These findings suggest new therapeutic opportunities for patients suffering from severe hereditary kidney diseases such as primary hyperoxaluria, and reveal a previously unappreciated general mechanism of kidney disease progression that may also contribute to conditions other than crystal nephropathy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.