Evidence map›Paper›PMID 24172537›Full record

ReviewMedical science monitor : international medical journal of experimental and clinical research2013

Genetic and molecular alterations in pancreatic cancer: implications for personalized medicine.

Yantian Fang, Qizhi Yao, Zongyou Chen, Jianbin Xiang, Fisher E William, Richard A Gibbs, Changyi Chen

Open access · hybridAbstract readReview
In one paragraph

Review in Medical science monitor : international medical journal of experimental and clinical research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Review
  3. New avenues for the treatment of immunotherapy-resistant pancreatic cancer.World journal of gastrointestinal oncology · 2024
    Review
  4. Review
  5. Review
  6. Current State of "Omics" Biomarkers in Pancreatic Cancer.Journal of personalized medicine · 2021
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Pancreatic Cancer Epidemiology, Detection, and Management.Gastroenterology research and practice · 2016
    Review
  15. Mitochondria and chloroplasts shared in animal and plant tissues: significance of communication.Medical science monitor : international medical journal of experimental and clinical research · 2015
    Review
  16. Expression of miR-148/152 family as potential biomarkers in non-small-cell lung cancer.Medical science monitor : international medical journal of experimental and clinical research · 2015
    Article
  17. Expression and clinical significance of microRNA-1246 in human oral squamous cell carcinoma.Medical science monitor : international medical journal of experimental and clinical research · 2015
    Article
  18. Personalized- and one- medicine: bioinformatics foundation in health and its economic feasibility.Medical science monitor : international medical journal of experimental and clinical research · 2015
    Article
  19. Aberrant expression of microRNA-26b and its prognostic potential in human cervical cancer.International journal of clinical and experimental pathology · 2015
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yantian FangMolecular Surgeon Research Center, Division of Surgical Research, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, U.S.A. and Department of General Surgery, Huashan Hospital, Fudan University, Shanghai, P.R. China.
Qizhi Yao
Zongyou Chen
Jianbin Xiang
Fisher E William
Richard A Gibbs
Changyi Chen
Michael E. DeBakey VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in human genomics and biotechnologies have profound impacts on medical research and clinical practice. Individual genomic information, including DNA sequences and gene expression profiles, can be used for prediction, prevention, diagnosis, and treatment for many complex diseases. Personalized medicine attempts to tailor medical care to individual patients by incorporating their genomic information. In a case of pancreatic cancer, the fourth leading cause of cancer death in the United States, alteration in many genes as well as molecular profiles in blood, pancreas tissue, and pancreas juice has recently been discovered to be closely associated with tumorigenesis or prognosis of the cancer. This review aims to summarize recent advances of important genes, proteins, and microRNAs that play a critical role in the pathogenesis of pancreatic cancer, and to provide implications for personalized medicine in pancreatic cancer.

Indexed as

Biomarkers, TumorGene Expression Regulation, NeoplasticGenomicsHumansMicroRNAsNeoplasm ProteinsOncogenesPancreatic NeoplasmsPrecision MedicineBiomarkers, TumorMicroRNAsNeoplasm Proteins

Identifiers

PMID24172537
PMCPMC3818103
OpenAlexW2043237658

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.