Evidence map›Paper›PMID 24172064›Full record

Trial reportHuman vaccines & immunotherapeutics2013

Influenza vaccination acceptance among diverse pregnant women and its impact on infant immunization.

Paula M Frew, Siyu Zhang, Diane S Saint-Victor, Ashley C Schade, Samantha Benedict, Maral Banan, Xiang Ren, Saad B Omer

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Human vaccines & immunotherapeutics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  14. Recruitment and retention of pregnant women into clinical research trials: an overview of challenges, facilitators, and best practices.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Paula M FrewDivision of Infectious Diseases; Department of Medicine; Emory University School of Medicine; Decatur, GA USA; Department of Behavioral Sciences and Health Education; Rollins School of Public Health; Emory University; Decatur, GA USA.
Siyu ZhangDivision of Infectious Diseases; Department of Medicine; Emory University School of Medicine; Decatur, GA USA; Department of Epidemiology; Rollins School of Public Health; Emory University; Decatur, GA USA.
Diane S Saint-VictorDivision of Infectious Diseases; Department of Medicine; Emory University School of Medicine; Decatur, GA USA; Hubert Department of Global Health; Rollins School of Public Health; Emory University; Decatur, GA USA.
Ashley C SchadeDivision of Allied Health; Emory University School of Medicine; Decatur, GA USA.
Samantha BenedictDivision of Infectious Diseases; Department of Medicine; Emory University School of Medicine; Decatur, GA USA; Department of Epidemiology; Rollins School of Public Health; Emory University; Decatur, GA USA.
Maral BananDivision of Infectious Diseases; Department of Medicine; Emory University School of Medicine; Decatur, GA USA; Department of Behavioral Sciences and Health Education; Rollins School of Public Health; Emory University; Decatur, GA USA.
Xiang RenDivision of Infectious Diseases; Department of Medicine; Emory University School of Medicine; Decatur, GA USA; Department of Epidemiology; Rollins School of Public Health; Emory University; Decatur, GA USA.
Saad B OmerHubert Department of Global Health; Rollins School of Public Health; Emory University; Decatur, GA USA.
Emory University · US

Funding

OPHPR CDC HHS 5P01TP000300OPHPR CDC HHS P01 TP000300
6 · The paper itself

Abstract

objectiveWe examined pregnant women's likelihood of vaccinating their infants against seasonal influenza via a randomized message framing study. Using Prospect Theory, we tested gain- and loss-frame message effects and demographic and psychosocial correlates of influenza immunization intention. We also explored interactions among pregnant women who viewed "Contagion" to understand cultural influences on message perception.

methodsPregnant women ages 18-50 participated in a randomized message framing study from September 2011 through May 2012 that included exposure to intervention or control messages, coupled with questionnaire completion. Venue-based sampling was used to recruit racial and ethnic minority female participants at locations throughout Atlanta, Georgia. Bivariate and multivariate analyses were conducted to evaluate key outcomes.

resultsThe study population (n = 261) included many lower income (≤ $20,000/yearly household earnings) pregnant participants (69.2%, n = 171) inclusive of Black/African Americans (88.5%, n = 230), Hispanic/Latinas (7.3%, n = 19), and Other/Multicultural women (4.2%, n = 11). Both gain [OR = 2.13, 90% CI: (1.120, 4.048)] and loss-frame messages [OR = 2.02, 90% CI: (1.083, 3.787)] were significantly associated with infant influenza vaccination intention compared with the control condition. Intention to immunize against influenza during pregnancy had a strong effect on intent to immunize infants [OR = 10.83, 90%CI: (4.923, 23.825)]. Those who had seen the feature film "Contagion" (n = 54, 20.69%) viewed gain- and loss-framed messages as appealing (x (2) = 6.03, p = 0.05), novel (x (2) = 6.24, p = 0.03), and easy to remember (x (2) = 16.33, P = 0.0003).

conclusionsIn this population, both gain- and loss-framed messages were positively associated with increased maternal intent to immunize infants against influenza. Message resonance was enhanced among those who saw the film "Contagion." Additionally, history of immunization was strongly associated with infant immunization intention. :

Indexed as

AdolescentAdultBehavior TherapyFemaleGeorgiaHumansInfantInfant, NewbornInfluenza, HumanInfluenza VaccinesMaleMiddle AgedPatient Acceptance of Health CarePregnancyPregnant PeopleVaccinationInfluenza Vaccinescontagionimmunization coverageinfluenza vaccinationmessage framingpregnant womenprospect theoryracial/ethnic minorities

Identifiers

PMID24172064
PMCPMC4162045
OpenAlexW1985501738

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.