Evidence map›Paper›PMID 24171817›Full record

ArticleWorld journal of surgical oncology2013

Breast adenomyoepithelioma: a case report with malignant proliferation of epithelial and myoepithelial elements.

Vincenzo Petrozza, Giulia Pasciuti, Alberto Pacchiarotti, Federica Tomao, Federica Zoratto, Luigi Rossi, Antonella Fontana, Fabiana Censi, Barbara Sardella, Claudio Di Cristofano and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in World journal of surgical oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

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  6. Adenomyoepithelioma of the Breast: A Report of 3 Cases.The American journal of case reports · 2022
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  16. Lobulated adenomyoepithelioma: a case report showing immunohistochemical profiles.International journal of clinical and experimental pathology · 2015
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  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Vincenzo Petrozza
Giulia Pasciuti
Alberto Pacchiarotti
Federica Tomao
Federica Zoratto
Luigi Rossi
Antonella Fontana
Fabiana Censi
Barbara Sardella
Claudio Di Cristofano
Natale PortaDepartment of Medical-Surgical Sciences and Biotechnologies, Histopathology Unit, Polo Pontino - Sapienza University of Rome, Latina, Italy. natale.porta@alice.it.
Carlo Della Rocca
Sapienza University of Rome · ITOspedale Santa Maria Goretti · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast adenomyoepithelioma is an unusual tumor characterized by a biphasic proliferation of epithelial and myoepithelial cells. Most breast adenomyoepitheliomas are considered to be benign or to have a low-grade malignant potential, characterized by propensity for local recurrence. Malignant changes arising in this lesion are extremely rare and may involve one or both cellular components. CASE REPORT: We discuss a case of a 60 year-old woman who began to experience pain in her right breast in January 2009. Breast ultrasound and mammography were performed showing a rounded, hypoechoic solid lesion with ill-defined margins in the right inner-inferior quadrant, suspicious of malignancy. Quadrantectomy of the inner-inferior quadrant of the right breast with sampling of ipsilateral axillary lymph nodes was performed. The histological analysis confirmed the diagnosis of adenomyoepithelioma with focal malignant change of the epithelial component, associated with high-grade malignant myoepithelial change. The patient was treated with adjuvant radiotherapy and her right breast received a dose of Gy 50 with a boost of Gy 10 to the tumor bed. At present, the patient shows no sign of tumor recurrence.

conclusionBreast malignant adenomyoepithelioma is a rare tumor which should be considered in the differential diagnosis of other solid breast lesions. Only few cases have been reported in the literature. Diagnosis, optimal therapy and predicting the outcome are problematic issues due to the rarity of this disease which appears to have hematogenous rather than lymphatic spread and usually occurs in primary tumors ≥ 1.6 cm in size.

Indexed as

Cell ProliferationAdenomyoepitheliomaBiomarkers, TumorBreast NeoplasmsEpithelial CellsFemaleHumansMiddle AgedPrognosisBiomarkers, Tumor

Identifiers

PMID24171817
PMCPMC3816540
OpenAlexW2137559443

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.