ArticleVirology journal2013
Identification of a new genotype of Torque Teno Mini virus.
Article in Virology journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 22 citations in OpenAlex.
- Longitudinal anellome dynamics in the upper respiratory tract of children with acute respiratory tract infections.Virus evolution · 2023Article
- Diversity and Long-Term Dynamics of Human Blood Anelloviruses.Journal of virology · 2022Article
- Taxonomic update for mammalian anelloviruses (family Anelloviridae).Archives of virology · 2021Article
- Genome Sequences of Novel Torque Teno Viruses Identified in Human Brain Tissue.Microbiology resource announcements · 2020Article
- Viral Metagenomics on Cerebrospinal Fluid.Genes · 2019Article
- Retrospective Analysis of Bacterial and Viral Co-Infections in Pneumocystis spp. Positive Lung Samples of Austrian Pigs with Pneumonia.PloS one · 2016Article
- A Novel Virus Causes Scale Drop Disease in Lates calcarifer.PLoS pathogens · 2015Article
- A systematic approach to novel virus discovery in emerging infectious disease outbreaks.The Journal of molecular diagnostics : JMD · 2015Review
- Article
- Culturing of respiratory viruses in well-differentiated pseudostratified human airway epithelium as a tool to detect unknown viruses.Influenza and other respiratory viruses · 2015Article
- Persistent viremia by a novel parvovirus in a slow loris (Nycticebus coucang) with diffuse histiocytic sarcoma.Frontiers in microbiology · 2014Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough human torque teno viruses (TTVs) were first discovered in 1997, still many associated aspects are not clarified yet. The viruses reveal a remarkable heterogeneity and it is possible that some genotypes are more pathogenic than others. The identification of all genotypes is essential to confirm previous pathogenicity data, and an unbiased search for novel viruses is needed to identify TTVs that might be related to disease.
methodThe virus discovery technique VIDISCA-454 was used to screen serum of 55 HIV-1 positive injecting drug users, from the Amsterdam Cohort Studies, in search for novel blood-blood transmittable viruses which are undetectable via normal diagnostics or panvirus-primer PCRs.
resultsA novel torque teno mini virus (TTMV) was identified in two patients and the sequence of the full genomes were determined. The virus is significantly different from the known TTMVs (< 40% amino acid identity in ORF1), yet it contains conserved characteristics that are also present in other TTMVs. The virus is chronically present in both patients, and these patients both suffered from a pneumococcal pneumonia during follow up and had extremely low B-cells counts.
conclusionWe describe a novel TTMV which we tentatively named TTMV-13. Further research is needed to address the epidemiology and pathogenicity of this novel virus.
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