Evidence map›Paper›PMID 24171023›Full record

ArticleIranian endodontic journal2013

Antimicrobial Efficacy of Mineral Trioxide Aggregate with and without Silver Nanoparticles.

Mohammad Samiei, Mohammad Aghazadeh, Mehrdad Lotfi, Sahar Shakoei, Zahra Aghazadeh, Seyyed Mahdi Vahid Pakdel

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Iranian endodontic journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohammad SamieiDental and Periodontal Research Center, Department of Endodontics, Dental School, Tabriz University of Medical Sciences, Tabriz, IR Iran.
Mohammad Aghazadeh
Mehrdad Lotfi
Sahar Shakoei
Zahra Aghazadeh
Seyyed Mahdi Vahid Pakdel

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMost current root-end filling materials do not provide a perfect seal. Thus, a microscopic space is likely to exist in the interface between walls of the root-end cavity and filling material, which allows microorganisms and their products to penetrate. In addition to good sealing ability and biocompatibility, root-end filling materials should ideally have some antimicrobial activity. Therefore, this in vitro study aimed to evaluate the antimicrobial properties of Angelus white mineral trioxide aggregate (MTA) and the mixture of MTA with silver nanoparticles (1% weight; MTA/SN). MATERIALS AND

methodsAntimicrobial properties of MTA and MTA/SN were tested by agar diffusion technique against Enterococcus faecalis, Pseudomonas aeruginosa, Staphylococcus aureus, and Candida albicans. The microbial inhibition zones around the materials were measured by a caliper with 0.1-mm accuracy. Student's t-test was used for comparison between the two groups in normal data distribution and Man-Whitney U test for non-normal distribution.

resultsStudent's t-test revealed that for E. faecalis, C. albicans, and P. aeruginosa, microbial inhibition zone of MTA/SN was significantly greater than that of MTA (P = 0.000). Mann-Whitney U test indicated no significant difference between the effect of MTA and MTA/SN on S. aureus (P > 0.05).

conclusionBased on the results of this study, adding silver nanoparticles to MTA improved its antimicrobial efficacy.

Indexed as

Antibacterial AgentsAntifungal AgentsMineral Trioxide AggregateNanoparticlesSilver

Identifiers

PMID24171023
PMCPMC3808675

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.