ArticleBioinorganic chemistry and applications2013
Synthesis and antioxidant activities of novel 5-chlorocurcumin, complemented by semiempirical calculations.
Article in Bioinorganic chemistry and applications, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Targeting cardiotoxicity: the potential ofIn silico pharmacology · 2025Article
- Multilayered Curcumin-Loaded Hydrogel Microcarriers with Antimicrobial Function.Molecules (Basel, Switzerland) · 2022Article
- Alignment Layer of Liquid Crystal Using Plant-Based Isoeugenol-Substituted Polystyrene.Polymers · 2021Article
- Coumarins as Potential Antioxidant Agents Complemented with Suggested Mechanisms and Approved by Molecular Modeling Studies.Molecules (Basel, Switzerland) · 2016Article
- Antioxidant Capacity Determination in Plants and Plant-Derived Products: A Review.Oxidative medicine and cellular longevity · 2016Review
- Antioxidant Activities of 4-Methylumbelliferone Derivatives.PloS one · 2016Article
- Efficient Catalyst One-Pot Synthesis of 7-(Aryl)-10,10-dimethyl-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione Derivatives Complemented by Antibacterial Activity.BioMed research international · 2016Article
- Hydrogen Peroxide Scavenging Activity of Novel Coumarins Synthesized Using Different Approaches.PloS one · 2015Article
- Electrochemical Study on Newly Synthesized Chlorocurcumin as an Inhibitor for Mild Steel Corrosion in Hydrochloric Acid.Materials (Basel, Switzerland) · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The novel curcumin derivative (1E,4Z,6E)-5-chloro-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one (5-chlorocurcumin) was prepared from natural curcumin. The newly synthesised compound was characterised by spectral studies (IR, 1H NMR, and 13C NMR). The free radical scavenging activity of 5-chlorocurcumin has been determined by measuring interaction with the stable free radical DPPH, and 5-chlorocurcumin has shown encouraging antioxidant activities. Theory calculations of the synthesised 5-chlorocurcumin were performed using molecular structures with optimised geometries. Molecular orbital calculations provided a detailed description of the orbitals, including spatial characteristics, nodal patterns, and the contributions of individual atoms.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.