ArticleHistochemistry and cell biology2014
Sox2 in the adult rat sensory nervous system.
Article in Histochemistry and cell biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 34 citations in OpenAlex.
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- Retrograde control of sympathetic neuron-satellite glia interactions by target-derived NGF signaling.Cell reports · 2025Article
- Distinctive glial cells in the dorsal root ganglion: their morphology and functions.Anatomical science international · 2025Review
- Article
- Morphological and phenotypical characteristics of porcine satellite glial cells of the dorsal root ganglia.Frontiers in neuroanatomy · 2022Article
- Distribution, fine structure, and three-dimensional innervation of lamellar corpuscles in rat plantar skin.Cell and tissue research · 2021Article
- Phenotypical peculiarities and species-specific differences of canine and murine satellite glial cells of spinal ganglia.Journal of cellular and molecular medicine · 2021Article
- Satellite Glial Cells Give Rise to Nociceptive Sensory Neurons.Stem cell reviews and reports · 2021Article
- The Clinical and Molecular Characteristics of Sex-Determining Region Y-Box 2 and its Prognostic Value in Breast Cancer: A Systematic Meta-Analysis.Breast care (Basel, Switzerland) · 2021Review
- ALK5 i II Accelerates Induction of Adipose-Derived Stem Cells toward Schwann Cells through a Non-Smad Signaling Pathway.Stem cells international · 2021Article
- More than just Stem Cells: Functional Roles of the Transcription Factor Sox2 in Differentiated Glia and Neurons.International journal of molecular sciences · 2019Review
- Identification of Hub Genes and Key Pathways Associated With Bipolar Disorder Based on Weighted Gene Co-expression Network Analysis.Frontiers in physiology · 2019Article
- Canine dorsal root ganglia satellite glial cells represent an exceptional cell population with astrocytic and oligodendrocytic properties.Scientific reports · 2017Article
- A Device for Ribbon Collection for Array Tomography with Scanning Electron Microscopy.Acta histochemica et cytochemica · 2017Article
- Evidence for a Notch1-mediated transition during olfactory ensheathing cell development.Journal of anatomy · 2016Article
- Temporal Analysis of Gene Expression in the Murine Schwann Cell Lineage and the Acutely Injured Postnatal Nerve.PloS one · 2016Article
- The Histochemistry and Cell Biology pandect: the year 2014 in review.Histochemistry and cell biology · 2015Review
- Contribution of Schwann Cells to Remyelination in a Naturally Occurring Canine Model of CNS Neuroinflammation.PloS one · 2015Article
Corrections and comments
- Erratum issuedKioke, Taro [corrected to Koike, Taro]
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sex-determining region Y (SRY)-box 2 (Sox2) is a member of the Sox family transcription factors. In the central nervous system, Sox2 is expressed in neural stem cells from neurogenic regions, and regulates stem cell proliferation and differentiation. In the peripheral nervous system, Sox2 is found only in the immature and dedifferentiated Schwann cells, and is involved in myelination inhibition or N-cadherin redistribution. In the present immunohistochemical study, we found that Sox2 is also expressed in other cells of the adult rat peripheral nervous system. Nuclear Sox2 was observed in all satellite glial cells, non-myelinating Schwann cells, and the majority of terminal Schwann cells that form lamellar corpuscles and longitudinal lanceolate endings. Sox2 was not found in myelinating Schwann cells and terminal Schwann cells of subepidermal free nerve endings. Satellite glial cells exhibit strong Sox2 immunoreactivity, whereas non-myelinating Schwann cells show weak immunoreactivity. RT-PCR confirmed the presence of Sox2 mRNA, indicating that the cells are likely Sox2 expressors. Our findings suggest that the role of Sox2 in the peripheral nervous system may be cell-type-dependent.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.