Evidence map›Paper›PMID 24170232›Full record

ArticleNetherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation2013

Basic concepts of fluid responsiveness.

T G V Cherpanath, B F Geerts, W K Lagrand, M J Schultz, A B J Groeneveld

2 registry-linked trialsOpen access · hybridAbstract read
In one paragraph

Article in Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02070276 nacompletednot on this mapstarted 2014, after this paper: background citation

Can Non Invasive Methods for Fluid Responsive Assessment Optimize Preventive Volemic Repletion in Order to Prevent Significant Hypotension After Spinal Anesthesia? A Randomized Trial

TypeinterventionalSponsorEnte Ospedaliero Cantonale, BellinzonaRan2014 to 2019Enrolled429ConditionsHypotension and Shock, Excessive Amount of Blood / Fluid InfusionArmsTrans-thoracic echocardiography, Passive Leg Raising Test
NCT02271477 nacompletednot on this mapstarted 2014, after this paper: background citation

Can Vena Cava Ultrasound Guided Volume Repletion Prevent Spinal Induced Significant Hypotension in Elective Surgical Patients? A Randomized, Case Control, Prospective Trial.

TypeinterventionalSponsorEnte Ospedaliero Cantonale, BellinzonaRan2014 to 2014Enrolled160ConditionsFluid Overload, Anesthesia, Adverse Effect, Spinal and Epidural, Regional Anesthesia MorbidityArmsUltrasound-guided volemic repletion
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. A Mini-Fluid Challenge to Predict Fluid Responsiveness in Swine.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
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  9. Observational
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  19. Defining human mean circulatory filling pressure in the intensive care unit.Journal of applied physiology (Bethesda, Md. : 1985) · 2020
    Article
  20. Competence of Intensivists in Focused Transthoracic Echocardiography in Intensive Care Unit: A Prospective Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

T G V CherpanathDepartment of Intensive Care Medicine, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands, T.G.Cherpanath@amc.uva.nl.
B F Geerts
W K Lagrand
M J Schultz
A B J Groeneveld
University of Amsterdam · NLErasmus University Rotterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Predicting fluid responsiveness, the response of stroke volume to fluid loading, is a relatively novel concept that aims to optimise circulation, and as such organ perfusion, while avoiding futile and potentially deleterious fluid administrations in critically ill patients. Dynamic parameters have shown to be superior in predicting the response to fluid loading compared with static cardiac filling pressures. However, in routine clinical practice the conditions necessary for dynamic parameters to predict fluid responsiveness are frequently not met. Passive leg raising as a means to alter biventricular preload in combination with subsequent measurement of the change in stroke volume can provide a fast and accurate way to guide fluid management in a broad population of critically ill patients.

Identifiers

PMID24170232
PMCPMC3833913
OpenAlexW2092432643

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.