SynthesisEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2014
Association of CD14 gene -159C/T polymorphism with allergic rhinitis risk: a meta-analysis.
Synthesis in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Association of the CD14 gene rs2569190 polymorphism with the risk of allergic rhinitis: a systematic review and meta-analysis.Scientific reports · 2026Pooled it
- Polymorphisms and AR: A Systematic Review and Meta-Analyses.Frontiers in genetics · 2022Pooled it
- Single nucleotide polymorphisms of IL-13 and CD14 genes in allergic rhinitis: a meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018Pooled it
- Pooled it
- Lack of association between CD14-159 C/T polymorphism and acute pancreatitis: a meta-analysis.International journal of clinical and experimental medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The -159C/T polymorphism in the CD14 gene has been implicated in susceptibility to allergic rhinitis (AR), but results were conflicting. The aim of this study is to investigate the association between the CD14-159C/T polymorphism and the risk of AR. All eligible case-control studies published up to July 2013 were identified by searching PubMed, Web of Science and CNKI. Pooled odds ratio with 95% confidence interval (95% CI) was used to access the strength of this association in fixed- or random-effects model. A total of seven case-control studies, including 887 cases and 889 controls, were selected. Overall, no significant association between the CD14-159C/T polymorphism and AR risk was found. Besides, stratified analysis with ethnicity and source of control also indicated that no significant association between CD14-159C/T and the risk of AR under all for genetic model was observed. This meta-analysis indicated that the CD14-159C/T polymorphism is not associated with AR risk.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.