Evidence map›Paper›PMID 24168177›Full record

Trial reportInternational journal of dermatology2014

Scabies community prevalence and mass drug administration in two Fijian villages.

Karin Haar, Lucia Romani, Raikanikoda Filimone, Kamal Kishore, Meciusela Tuicakau, Josefa Koroivueta, John M Kaldor, Handan Wand, Andrew Steer, Margot Whitfeld

Open access · bronzeAbstract readClinical TrialComparative StudyMulticenter Study
In one paragraph

Trial report in International journal of dermatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 4 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Prevalence and determinants of scabies: A global systematic review and meta-analysis.Tropical medicine & international health : TM & IH · 2024
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  13. Mass drug administration for endemic scabies: a systematic review.Tropical diseases, travel medicine and vaccines · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Karin HaarUniversity of Sydney, New South Wales, Australia.
Lucia Romani
Raikanikoda Filimone
Kamal Kishore
Meciusela Tuicakau
Josefa Koroivueta
John M Kaldor
Handan Wand
Andrew Steer
Margot Whitfeld
Ministry Of Health · FJUNSW Sydney · AUFiji National University · FJSt Vincent's Hospital Sydney · AUUniversity of Melbourne · AUUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundScabies has been estimated to affect approximately 300 million people worldwide each year. Scabies rates are high and pose a significant public health problem in Fiji. Community-based comparison treatment trials have not been undertaken. We estimated scabies prevalence and compared the efficacy and tolerability of mass drug administration (MDA) of benzyl benzoate lotion (BB) or oral ivermectin (IVM) in two villages in Fiji.

methodsA prospective MDA trial was undertaken in two Fijian villages, comparing three daily applications of BB with single dose IVM or permethrin cream for those aged under two years. The therapies were offered to all community members regardless of the presence of scabies or its symptoms. The difference in prevalence was measured before and after the intervention and absolute risk reduction (ARR) and relative risk (RR) calculated.

resultsIn the BB group, there were 572 eligible participants, of whom 435 (76%) enrolled and 201 (46%) returned for follow-up. In the IVM group, there were 667 eligible participants, of whom 325 (49%) enrolled and 126 (39%) returned. Scabies prevalence was lower after the intervention in both groups. It fell from 37.9 to 20.0% (ARR 18.0%; RR 0.52) in the BB group and from 23.7 to 9.5% (ARR 14.2%; RR 0.40) in the IVM group.

conclusionsOur study provides proof of principle that MDA for scabies can reduce scabies prevalence at the community level, and that there was no significant difference in this trial between BB and oral IVM.

Indexed as

AdolescentAdultBenzoatesChildChild, PreschoolChi-Square DistributionConfidence IntervalsDeveloping CountriesDose-Response Relationship, DrugDrug Administration ScheduleFemaleFijiFollow-Up StudiesHumansIvermectinMaleBenzoatesbenzyl benzoateIvermectin

Identifiers

PMID24168177
PMCPMC4282484
OpenAlexW2162950025

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.