ArticlePloS one2013
Identification of novel viruses using VirusHunter--an automated data analysis pipeline.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed.
- Nanopore sequencing in veterinary medicine: from concepts to clinical applications.Frontiers in cellular and infection microbiology · 2025Review
- Orbivirus RNA in a Banana Serotine (Afronycteris nanus) Bat in the Republic of the Congo.EcoHealth · 2022Article
- LABRADOR-A Computational Workflow for Virus Detection in High-Throughput Sequencing Data.Viruses · 2021Article
- Towards the validation of high-throughput sequencing (HTS) for routine plant virus diagnostics: measurement of variation linked to HTS detection of citrus viruses and viroids.Virology journal · 2021Article
- High Throughput Sequencing for the Detection and Characterization of RNA Viruses.Frontiers in microbiology · 2021Review
- 2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales.Archives of virology · 2020Article
- Review
- Article
- Can Bats Serve as Reservoirs for Arboviruses?Viruses · 2019Review
- Discovery and Characterization of Bukakata orbivirus (Viruses · 2019Article
- A new approach for detecting adventitious viruses shows Sf-rhabdovirus-negative Sf-RVN cells are suitable for safe biologicals production.BMC biotechnology · 2018Article
- Overview of Virus Metagenomic Classification Methods and Their Biological Applications.Frontiers in microbiology · 2018Review
- A Murine Herpesvirus Closely Related to Ubiquitous Human Herpesviruses Causes T-Cell Depletion.Journal of virology · 2017Article
- Statoviruses, A novel taxon of RNA viruses present in the gastrointestinal tracts of diverse mammals.Virology · 2017Article
- Next-generation Sequencing of the DNA Virome from Fecal Samples.Bio-protocol · 2017Article
- VirusSeeker, a computational pipeline for virus discovery and virome composition analysis.Virology · 2017Article
- HIV-associated changes in the enteric microbial community: potential role in loss of homeostasis and development of systemic inflammation.Current opinion in infectious diseases · 2017Review
- Viral Diagnostics in Plants Using Next Generation Sequencing: Computational Analysis in Practice.Frontiers in plant science · 2017Review
- Challenges in the analysis of viral metagenomes.Virus evolution · 2016Review
- Divergent viral presentation among human tumors and adjacent normal tissues.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Quick and accurate identification of microbial pathogens is essential for both diagnosis and response to emerging infectious diseases. The advent of next-generation sequencing technology offers an unprecedented platform for rapid sequencing-based identification of novel viruses. We have developed a customized bioinformatics data analysis pipeline, VirusHunter, for the analysis of Roche/454 and other long read Next generation sequencing platform data. To illustrate the utility of VirusHunter, we performed Roche/454 GS FLX titanium sequencing on two unclassified virus isolates from the World Reference Center for Emerging Viruses and Arboviruses (WRCEVA). VirusHunter identified sequences derived from a novel bunyavirus and a novel reovirus in the two samples respectively. Further sequence analysis demonstrated that the viruses were novel members of the Phlebovirus and Orbivirus genera. Both Phlebovirus and Orbivirus genera include many economic important viruses or serious human pathogens.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.