Trial reportPloS one2013
Sagittal abdominal diameter is an independent predictor of all-cause and cardiovascular mortality in incident peritoneal dialysis patients.
Trial report in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 20 citations in OpenAlex.
- Opportunistic measurement of sagittal abdominal diameter with bone densitometry predicts death and cardiovascular events.JBMR plus · 2025Article
- Association between sagittal abdominal diameter-to-height ratio and all-cause mortality among adults in the United States: a longitudinal study.Archives of public health = Archives belges de sante publique · 2024Article
- Dietary acid load decreases with age and is associated with sagittal abdominal diameter: a nationally representative quantification study in US adults.Aging clinical and experimental research · 2023Article
- Sagittal abdominal diameter and its socioeconomic correlates: perspective of sex differences.BMC public health · 2021Article
- Interaction between central obesity and frailty on the clinical outcome of peritoneal dialysis patients.PloS one · 2020Article
- Sagittal abdominal diameter and Framingham risk score in non-dialysis chronic kidney disease patients.International urology and nephrology · 2018Article
- Comparison of adiposity indicators associated with fasting-state insulinemia, triglyceridemia, and related risk biomarkers in a nationally representative, adult population.Diabetes research and clinical practice · 2018Article
- Relationship between sudden natural death and abdominal fat evaluated on postmortem CT scans.Obesity science & practice · 2017Article
- Abdominal Obesity and Mortality in Continuous Ambulatory Peritoneal Dialysis Patients.Electrolyte & blood pressure : E & BP · 2015Article
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUNDS AND
aimsVisceral fat has a crucial role in the development and progression of cardiovascular disease, the major cause of death in end-stage renal disease (ESRD). Although sagittal abdominal diameter (SAD), as an index of visceral fat, significantly correlated with mortality in the general population, the impact of SAD on clinical outcomes has never been explored in ESRD patients. Therefore, we sought to elucidate the prognostic value of SAD in incident peritoneal dialysis (PD) patients.
methodsWe prospectively determined SAD by lateral abdominal X-ray at PD initiation, and evaluated the association of SAD with all-cause and cardiovascular mortality in 418 incident PD patients.
resultsThe mean SAD was 24.5 ± 4.3 cm, and during a mean follow-up of 39.4 months, 97 patients (23.2%) died, and 49.4% of them died due to cardiovascular disease. SAD was a significant independent predictor of all-cause [3rd versus 1st tertile, HR (hazard ratio): 3.333, 95% CI (confidence interval): 1.514-7.388, P = 0.01; per 1 cm increase, HR: 1.071, 95% CI: 1.005-1.141, P = 0.03] and cardiovascular mortality (3rd versus 1st tertile, HR: 8.021, 95% CI: 1.994-32.273, P = 0.01; per 1 cm increase, HR: 1.106, 95% CI: 1.007-1.214, P = 0.03). Multivariate fractional polynomial analysis also showed that all-cause and cardiovascular mortality risk increased steadily with higher SAD values. In addition, SAD provided higher predictive value for all-cause (AUC: 0.691 vs. 0.547, P<0.001) and cardiovascular mortality (AUC: 0.644 vs. 0.483, P<0.001) than body mass index (BMI). Subgroup analysis revealed higher SAD (≥ 24.2 cm) was significantly associated with all-cause mortality in men, women, younger patients (<65 years), and patients with lower BMI (<22.3 kg/m(2)).
conclusionsSAD determined by lateral abdominal X-ray at PD initiation was a significant independent predictor of all-cause and cardiovascular mortality in incident PD patients. Estimating visceral fat by SAD could be useful to stratify mortality risk in these patients.
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