Evidence map›Paper›PMID 24167354›Full record

ArticleDisease markers2013

Relationship between acute phase proteins and serum fatty acid composition in morbidly obese patients.

Ricardo Fernandes, Bruna Teles Soares Beserra, Raphael Salles Granato Cunha, Elaine Hillesheim, Carolina de Quadros Camargo, Danielle Cristina Tonello Pequito, Isabela Coelho de Castro, Luiz Cláudio Fernandes, Everson Araújo Nunes, Erasmo Benício Santos de Moraes Trindade

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ricardo FernandesPost-Graduate Program in Nutrition, Federal University of Santa Catarina, Trindade Campus, 88040-900 Florianópolis, SC, Brazil.
Bruna Teles Soares Beserra
Raphael Salles Granato Cunha
Elaine Hillesheim
Carolina de Quadros Camargo
Danielle Cristina Tonello Pequito
Isabela Coelho de Castro
Luiz Cláudio Fernandes
Everson Araújo Nunes
Erasmo Benício Santos de Moraes Trindade
Universidade Federal de Santa Catarina · BRUniversidade Federal do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity is considered a low-grade inflammatory state and has been associated with increased acute phase proteins as well as changes in serum fatty acids. Few studies have assessed associations between acute phase proteins and serum fatty acids in morbidly obese patients.

objectiveTo investigate the relationship between acute phase proteins (C-Reactive Protein, Orosomucoid, and Albumin) and serum fatty acids in morbidly obese patients.

methodsTwenty-two morbidly obese patients were enrolled in this study. Biochemical and clinical data were obtained before bariatric surgery, and fatty acids measured in preoperative serum.

resultsOrosomucoid was negatively correlated with lauric acid (P = 0.027) and eicosapentaenoic acid (EPA) (P = 0.037) and positively with arachidonic acid (AA) (P = 0.035), AA/EPA ratio (P = 0.005), and n-6/n-3 polyunsaturated fatty acids ratio (P = 0.035). C-Reactive Protein (CRP) was negatively correlated with lauric acid (P = 0.048), and both CRP and CRP/Albumin ratio were negatively correlated with margaric acid (P = 0.010, P = 0.008, resp.). Albumin was positively correlated with EPA (P = 0.027) and margaric acid (P = 0.008). Other correlations were not statistically significant.

conclusionOur findings suggest that serum fatty acids are linked to acute phase proteins in morbidly obese patients.

Indexed as

Acute-Phase ProteinsAdultBiomarkersFatty Acids, Omega-3Fatty Acids, Omega-6FemaleHumansLauric AcidsMaleMiddle AgedObesity, MorbidAcute-Phase ProteinsBiomarkersFatty Acids, Omega-3Fatty Acids, Omega-6lauric acidLauric Acids

Identifiers

PMID24167354
PMCPMC3774976
OpenAlexW2035418257

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.