ArticleAngewandte Chemie (International ed. in English)2013
De novo generation of singlet oxygen and ammine ligands by photoactivation of a platinum anticancer complex.
Article in Angewandte Chemie (International ed. in English), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 73 citations in OpenAlex.
- Colorectal Cancer at the Crossroads: The Good, the Bad, and the Future of Platinum-Based Drugs.Chemical reviews · 2025Review
- Excited-StateInorganic chemistry · 2025Article
- Tuning the photoactivated anticancer activity of Pt(iv) compoundsChemical science · 2024Article
- Photoinduced Reductive C-C and C-Heteroatom Couplings from Bis-cyclometalated Pt(IV) Alkynyl Complexes.Inorganic chemistry · 2023Article
- DFT Study on the Substituent Effect of Anticancer Picoline-Diazido-Pt(IV) Compounds.Frontiers in oncology · 2021Article
- Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials.Chemical reviews · 2020Article
- Induction of immunogenic cell death in cancer cells by a photoactivated platinum(IV) prodrug.Inorganic chemistry frontiers · 2020Article
- New Designs for Phototherapeutic Transition Metal Complexes.Angewandte Chemie (International ed. in English) · 2020Review
- A novel Pt(iv) mono azido mono triazolato complex evolves azidyl radicals following irradiation with visible light.Dalton transactions (Cambridge, England : 2003) · 2019Article
- Photoactivatable platinum anticancer complex can generate tryptophan radicals.Chemical communications (Cambridge, England) · 2018Article
- Photoactivatable Cell-Selective Dinuclear trans-Diazidoplatinum(IV) Anticancer Prodrugs.Inorganic chemistry · 2018Article
- Platinum(iv) azido complexes undergo copper-free click reactions with alkynes.Dalton transactions (Cambridge, England : 2003) · 2018Article
- Spectroscopic Studies on Photoinduced Reactions of the Anticancer Prodrug, trans,trans,trans-[Pt(NChemistry (Weinheim an der Bergstrasse, Germany) · 2018Article
- Photocontrol of Antibacterial Activity: Shifting from UV to Red Light Activation.Journal of the American Chemical Society · 2017Article
- Comprehensive Vibrational Spectroscopic Investigation of trans,trans,trans-[Pt(N3)2(OH)2(py)2], a Pt(IV) Diazido Anticancer Prodrug Candidate.Inorganic chemistry · 2016Article
- The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs.Chemical reviews · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
Worth the excitement: Highly reactive oxygen and nitrogen species are generated by photoactivation of the anticancer platinum(IV) complex trans,trans,trans-[Pt(N3 )2 (OH)2 (MA)(Py)] (MA=methylamine, Py=pyridine). Singlet oxygen is formed from the hydroxido ligands and not from dissolved oxygen, and ammine ligands are products from the conversion of azido ligands to nitrenes. Both processes can induce oxidation of guanine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.